Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29965298 | 0.85 | OPRD1 (0.49) | — | |
| SCHEMBL30167976 | 0.83 | MMP1 (0.48) | MMP3ALDH1A1RENMMP1MMP9 | |
| SCHEMBL29964886 | 0.81 | ALDH1A1 (0.42) | MMP3ALDH1A1MMP1MMP9MEN1 | |
| SCHEMBL30167978 | 0.77 | PTPN1 (0.46) | MMP3MMP1MMP9KMT2AERAP2 | |
| SCHEMBL30167975 | 0.76 | PTPN1 (0.45) | MMP3MMP1 | |
| SCHEMBL17542012 | 0.74 | KIF11 (0.48) | ALDH1A1MEN1KMT2AGAANPC1 | |
| SCHEMBL17542010 | 0.74 | KIF11 (0.48) | ALDH1A1MEN1KMT2AGAANPC1 | |
| SCHEMBL30100119 | 0.72 | FPR2 (0.50) | MMP3ALDH1A1KMT2A | |
| SCHEMBL30990575 | 0.71 | CCKBR (0.49) | REN | |
| SCHEMBL29964989 | 0.69 | KIF11 (0.50) | ALDH1A1MEN1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4092038-A1 | OPIOID AGONIST PEPTIDES AND USES THEREOF | Protagonist Therapeutics, Inc. (US) | 2022-11-23 | — | — | EP | disclosed |