SCHEMBL30167975

SCHEMBL30167975

COc1ccc(C(N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
OPRM1 P35372 1/20 0.44
OPRD1 P41143 1/20 0.44
ATM Q13315 1/20 0.44
GHSR Q92847 1/20 0.44
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
CTSL P07711 1/20 0.43
FURIN P09958 1/20 0.43
FPR2 P25090 1/20 0.42
MMP1 P03956 2/20 0.42
MMP3 P08254 1/20 0.42
HRH1 P35367 1/20 0.42
SSTR3 P32745 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30167978 0.97 PTPN1 (0.46) PTPN1OPRM1OPRD1ATMCTSL
SCHEMBL30100119 0.93 FPR2 (0.50) FPR2MMP3
SCHEMBL30990575 0.86 CCKBR (0.49) PTPN1
SCHEMBL30167976 0.84 MMP1 (0.48) PTPN1OPRM1OPRD1ATMFPR2
SCHEMBL7603846 0.83 KIF11 (0.50) PRSS1PRSS2PRSS3FPR2
SCHEMBL17274480 0.83 KIF11 (0.50) PRSS1PRSS2PRSS3FPR2
SCHEMBL20964465 0.80 PRSS1 (0.54) PTPN1PRSS1PRSS2PRSS3CTSL
SCHEMBL26439541 0.78 GHSR (0.53) GHSRCTSLFURINMMP1MMP3
SCHEMBL29965298 0.78 OPRD1 (0.49) PTPN1OPRM1OPRD1
SCHEMBL29964895 0.76 MMP3 (0.44) MMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548913-B2 Therapeutic compositions including peptides and uses thereof STEALTH BIOTHERAPEUTICS INC. (US) 2023-01-10 US claimed
US-11548913-B2 Therapeutic compositions including peptides and uses thereof STEALTH BIOTHERAPEUTICS INC. (US) 2023-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548913-B2 Therapeutic compositions including peptides and uses thereof VIP, IAPP, TNNI3 PTPN1 1541/4885OPRM1 2534/4885OPRD1 3399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.