Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167975 | 0.97 | PTPN1 (0.45) | PTPN1OPRM1OPRD1ATMCTSL | |
| SCHEMBL30100119 | 0.90 | FPR2 (0.50) | FPR2MMP3GNPATKMT2A | |
| SCHEMBL30990575 | 0.85 | CCKBR (0.49) | PTPN1 | |
| SCHEMBL30167976 | 0.85 | MMP1 (0.48) | PTPN1OPRM1OPRD1ATMFPR2 | |
| SCHEMBL7603846 | 0.79 | KIF11 (0.50) | FPR2MMP9KIF11KCNH2 | |
| SCHEMBL17274480 | 0.79 | KIF11 (0.50) | FPR2MMP9KIF11KCNH2 | |
| SCHEMBL29965298 | 0.79 | OPRD1 (0.49) | PTPN1OPRM1OPRD1 | |
| SCHEMBL20072307 | 0.78 | GNPAT (0.52) | CTSLMMP1GNPAT | |
| SCHEMBL29964895 | 0.77 | MMP3 (0.44) | MMP1MMP3MMP9ERAP2ERAP1 | |
| SCHEMBL20964465 | 0.77 | PRSS1 (0.54) | PTPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548913-B2 | Therapeutic compositions including peptides and uses thereof | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548913-B2 | Therapeutic compositions including peptides and uses thereof | VIP, IAPP, TNNI3 | PTPN1 1541/4885OPRM1 2534/4885OPRD1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.