Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30773497 | 0.82 | HTR1A (0.55) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL2389927 | 0.82 | HTR1A (0.55) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL6293887 | 0.79 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL6289414 | 0.79 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL6289399 | 0.79 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL6293091 | 0.79 | HTR1A (0.59) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL29554 | 0.77 | HSPB1 (0.46) | HSPB1 | |
| SCHEMBL6293051 | 0.75 | PARP10 (0.66) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL702582 | 0.73 | PARP10 (0.58) | HTR1ASLC6A2SLC6A3SLC6A4ALDH1A1 | |
| SCHEMBL6289863 | 0.73 | PARP10 (0.63) | HTR1ASLC6A2SLC6A3ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9241487-B2 | Pyrimidine derivatives and use thereof as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| CN-103180301-B | 5-iodo triazole derivative | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| US-9095136-B2 | 2-IODO imidazole-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2609088-B1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-8969248-B2 | 5-iodotriazole derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| CN-104066725-A | Novel heterocyclic alkanol derivatives | BAYER IP GMBH | 2014-09-24 | — | — | CN | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| CN-104039146-A | 2-iodo Imidazole-derivatives | BAYER IP GMBH | 2014-09-10 | — | — | CN | disclosed |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| CN-103391926-A | Pyrimidine derivatives and use thereof as pesticides | BAYER IP GMBH | 2013-11-13 | — | — | CN | disclosed |
| EP-2646418-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2609088-A1 | 5-IODO-TRIAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| CN-103180301-A | 5-iodo-triazole derivatives | BAYER CROPSCIENCE AG | 2013-06-26 | — | — | CN | disclosed |
| US-20120220638-A1 | 5-Iodotriazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2012072547-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012025506-A1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | CIP2A, ING2, AZI2 | HTR1A 3848/4885SLC6A2 4614/4885SLC6A3 4423/4885 |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | TYMP, TYMS, UMPS | HTR1A 3588/4885SLC6A2 4458/4885SLC6A3 3862/4885 |
| US-20120220638-A1 | 5-Iodotriazole derivatives | INMT, IGFBP5, HDHD5 | HTR1A 2432/4885SLC6A2 4205/4885SLC6A3 3072/4885 |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | HTR1A 3543/4885SLC6A2 4853/4885SLC6A3 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.