Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456772 | 0.84 | TRPA1 (0.56) | HSPB1TRPA1AREPAS1 | |
| SCHEMBL29965 | 0.77 | HTR1A (0.47) | HSPB1 | |
| SCHEMBL22681688 | 0.71 | MAPK14 (0.55) | HSPB1TRPA1MAPK14ARPTGS2 | |
| SCHEMBL10943638 | 0.70 | BRD4 (0.41) | HSPB1TRPA1MAPK14EPAS1PTGS2 | |
| SCHEMBL1547178 | 0.70 | CES2 (0.43) | HSPB1TRPA1 | |
| SCHEMBL22060037 | 0.70 | ALDH1A1 (0.42) | HSPB1TRPA1 | |
| SCHEMBL16392368 | 0.70 | IDO1 (0.48) | HSPB1TRPA1 | |
| SCHEMBL29366053 | 0.70 | LMNA (0.53) | TRPA1 | |
| SCHEMBL1484426 | 0.70 | IDO1 (0.43) | HSPB1TRPA1 | |
| SCHEMBL197204 | 0.70 | LMNA (0.53) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9241487-B2 | Pyrimidine derivatives and use thereof as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-26 | — | — | US | disclosed |
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-9095136-B2 | 2-IODO imidazole-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2609088-B1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER IP GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-8969248-B2 | 5-iodotriazole derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| EP-2782904-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| EP-2646418-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | Bayer Intellectual Property GmbH (DE) | 2013-10-09 | — | — | EP | disclosed |
| EP-2609088-A1 | 5-IODO-TRIAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2013076227-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-30 | — | — | WO | disclosed |
| US-20120220638-A1 | 5-Iodotriazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2012072547-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012025506-A1 | 5-IODO-TRIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336232-A1 | 2-IODO IMIDAZOLE-DERIVATIVES | CIP2A, ING2, AZI2 | HSPB1 1581/4885TRPA1 2925/4885MAPK14 931/4885 |
| US-20140031373-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS PESTICIDES | TYMP, TYMS, UMPS | HSPB1 3371/4885TRPA1 1236/4885MAPK14 2896/4885 |
| US-20120220638-A1 | 5-Iodotriazole derivatives | INMT, IGFBP5, HDHD5 | HSPB1 2723/4885TRPA1 3157/4885MAPK14 1922/4885 |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | HSPB1 3294/4885TRPA1 893/4885MAPK14 1196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.