Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.39 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1023250 | 1.00 | MAPT (0.40) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| SCHEMBL8032089 | 0.99 | MAPT (0.41) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| SCHEMBL9412150 | 0.86 | NSD2 (0.42) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| Hydrochloric Acid SCHEMBL1021043 | 0.85 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| Hydrochloric Acid SCHEMBL29381202 | 0.85 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| Chloromethane SCHEMBL9412215 | 0.84 | NSD2 (0.41) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| SCHEMBL4324222 | 0.84 | ALDH1A1 (0.40) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| Hydrochloric Acid SCHEMBL29381615 | 0.82 | MAPT (0.39) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| Hydrochloric Acid SCHEMBL1022456 | 0.82 | MAPT (0.39) | MAPTLMNAALDH1A1POLBHCRTR1 | |
| Hydrochloric Acid SCHEMBL29381395 | 0.82 | MAPT (0.41) | MAPTLMNAALDH1A1POLBHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250213433-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | KURARAY NORITAKE DENTAL INC. (JP) | 2025-07-03 | — | — | US | disclosed |
| EP-4578439-A1 | DENTAL ADHESIVE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2025-07-02 | — | — | EP | disclosed |
| EP-4505993-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | Kuraray Noritake Dental Inc. (JP) | 2025-02-12 | — | — | EP | disclosed |
| EP-4464301-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | Kuraray Noritake Dental Inc. (JP) | 2024-11-20 | — | — | EP | disclosed |
| US-20240315929-A1 | DENTAL ADHESIVE KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2024-09-26 | — | — | US | disclosed |
| US-20240245584-A1 | DENTAL FILLING KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2024-07-25 | — | — | US | disclosed |
| US-20240074946-A1 | DENTAL COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2024-03-07 | — | — | US | disclosed |
| EP-4268796-A1 | DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| EP-4268791-A1 | ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME | Kuraray Noritake Dental Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| EP-4268795-A1 | DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023191113-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | クラレノリタケデンタル株式会社 | 2023-10-05 | — | — | WO | disclosed |
| WO-2023136337-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | クラレノリタケデンタル株式会社 | 2023-07-20 | — | — | WO | disclosed |
| EP-3782598-B1 | ADHESIVE COMPOSITION FOR DENTAL USE | KURARAY NORITAKE DENTAL INC (JP) | 2023-02-15 | — | — | EP | disclosed |
| EP-3677241-B1 | NON-SOLVENT-TYPE ADHESIVE COMPOSITION FOR DENTAL USE | KURARAY NORITAKE DENTAL INC (JP) | 2023-02-15 | — | — | EP | disclosed |
| US-11547639-B2 | Dental composition containing platinum nanoparticles | KURARAY NORITAKE DENTAL INC. (JP) | 2023-01-10 | — | — | US | disclosed |
| WO-2022270601-A1 | DENTAL ADHESIVE KIT | クラレノリタケデンタル株式会社 | 2022-12-29 | — | — | WO | disclosed |
| WO-2022230909-A1 | DENTAL FILLING KIT | クラレノリタケデンタル株式会社 | 2022-11-03 | — | — | WO | disclosed |
| WO-2022220250-A1 | DENTAL FILLING KIT | クラレノリタケデンタル株式会社 | 2022-10-20 | — | — | WO | disclosed |
| US-11452674-B2 | Non-solvent dental adhesive composition | KURARAY NORITAKE DENTAL INC. (JP) | 2022-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240074946-A1 | DENTAL COMPOSITION | PIEZO1, TAS2R42, EIF2B3 | CHRM2 4654/4885CHRM1 4547/4885SLC6A2 4622/4885 |
| US-11452674-B2 | Non-solvent dental adhesive composition | CDH1, VCL, MACF1 | CHRM2 3922/4885CHRM1 2609/4885SLC6A2 2874/4885 |
| US-20250213433-A1 | SELF-ADHESIVE COMPOSITE RESIN FOR DENTAL USE | CDH1, MACF1, ICAM1 | CHRM2 3670/4885CHRM1 2771/4885SLC6A2 3463/4885 |
| US-20240245584-A1 | DENTAL FILLING KIT | KIT, CAD, CDH1 | CHRM2 3521/4885CHRM1 1265/4885SLC6A2 4702/4885 |
| US-20240315929-A1 | DENTAL ADHESIVE KIT | ITGA1, CAD, ITGA2 | CHRM2 2331/4885CHRM1 935/4885SLC6A2 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.