Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.51 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.48 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.48 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.46 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.46 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594466 | 0.90 | CYP1A2 (0.52) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL29637806 | 0.81 | PHLPP2 (0.53) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL29678208 | 0.80 | ENPP2 (0.55) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL7603593 | 0.77 | CYP1A2 (0.62) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL29723425 | 0.74 | ENPP2 (0.75) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL12573539 | 0.74 | ENPP2 (0.75) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL344209 | 0.74 | PHLPP2 (0.70) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL29377534 | 0.74 | PHLPP2 (0.70) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL113323 | 0.74 | PHLPP2 (0.70) | PHLPP2ENPP2SENP2SUMO2SUMO1 | |
| SCHEMBL186095 | 0.74 | PHLPP2 (0.70) | PHLPP2ENPP2SENP2SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11554594-B2 | Ink jet method and ink jet recording apparatus | SEIKO EPSON CORPORATION | 2023-01-17 | — | — | US | disclosed |