Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.43 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681520 | 1.00 | PTK2B (0.43) | PTK2BHSD17B14CES2CES1ACLY | |
| Potassium Ion SCHEMBL2176793 | 0.96 | PTK2B (0.43) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL250118 | 0.81 | PTK2B (0.45) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL1681521 | 0.79 | PTK2B (0.44) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL5030349 | 0.79 | PTK2B (0.44) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL2489571 | 0.79 | PTK2B (0.44) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL14547178 | 0.79 | PTK2B (0.44) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL1682113 | 0.79 | PTK2B (0.44) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL2176795 | 0.79 | PTK2B (0.44) | PTK2BHSD17B14CES2CES1ACLY | |
| SCHEMBL4365595 | 0.78 | MMP2 (0.49) | SMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118202088-A | Electrode structure for water electrolysis, membrane electrode assembly for water electrolysis, and water electrolysis device | 东丽株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-111886734-B | Electrolyte membrane | 东丽株式会社 | 2024-03-08 | — | — | CN | disclosed |
| CN-117098798-A | Polyelectrolyte material, polyelectrolyte molded body using same, electrolyte membrane with catalyst layer, membrane electrode assembly, solid polymer fuel cell, and water-splitting hydrogen generator | 东丽株式会社 | 2023-11-21 | — | — | CN | disclosed |
| CN-116065188-A | Composite electrolyte membrane | 东丽株式会社 | 2023-05-05 | — | — | CN | disclosed |
| CN-112204071-B | Composite electrolyte membrane | 东丽株式会社 | 2023-02-17 | — | — | CN | disclosed |