Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704263 | 0.82 | RAB9A (0.57) | ALOX5APPNPC1RAB9AMAPT | |
| SCHEMBL13379899 | 0.81 | NPC1 (0.65) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL3042867 | 0.81 | NPC1 (0.55) | ALOX5APPNPC1RAB9AMAPT | |
| SCHEMBL3041535 | 0.81 | ALOX5 (0.50) | ALOX5APPNPC1RAB9AMAPT | |
| SCHEMBL3048501 | 0.81 | ALOX5 (0.50) | ALOX5APPNPC1RAB9AMAPT | |
| SCHEMBL13290986 | 0.81 | ALOX5 (0.50) | ALOX5APPNPC1RAB9AMAPT | |
| SCHEMBL13290970 | 0.81 | NPC1 (0.55) | ALOX5APPNPC1RAB9AMAPT | |
| SCHEMBL3042432 | 0.81 | NPC1 (0.55) | ALOX5NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL3032584 | 0.81 | NPC1 (0.69) | ALOX5NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL3045365 | 0.79 | ALOX5 (0.49) | ALOX5NPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666754-B1 | FULLY CONTINUOUS FLOW PRODUCTION PROCESS FOR DIRECTLY PREPARING ORGANIC PEROXIDE FROM ALCOHOL OR ALKANE | SHANGHAI HYBRID CHEM TECH (CN) | 2023-03-29 | — | — | EP | claimed |
| US-10919849-B2 | Online continuous flow process for the preparation of organic peroxides direct from alcohols or alkanes | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2021-02-16 | — | — | US | claimed |
| US-20200199068-A1 | ONLINE CONTINUOUS FLOW PROCESS FOR THE PREPARATION OF ORGANIC PEROXIDES DIRECT FROM ALCOHOLS OR ALKANES | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2020-06-25 | — | — | US | claimed |
| EP-3666755-A1 | ONLINE FULL CONTINUOUS FLOW PRODUCTION PROCESS FOR DIRECTLY PREPARING ORGANIC PEROXIDE WITH HYDROGEN PEROXIDE AS RAW MATERIAL | Shanghai Hybrid-Chem Technologies (CN) | 2020-06-17 | — | — | EP | claimed |
| EP-3666754-A1 | ONLINE FULLY CONTINUOUS FLOW PRODUCTION PROCESS FOR DIRECTLY PREPARING ORGANIC PEROXIDE FROM ALCOHOL OR ALKANE | Shanghai Hybrid-Chem Technologies (CN) | 2020-06-17 | — | — | EP | claimed |
| US-11840517-B2 | Lappaconitine derivative with analgesic activity, and preparation and application thereof | SOUTHWEST JIAOTONG UNIVERSITY (CN) | 2023-12-12 | — | — | US | disclosed |
| EP-3666754-B1 | FULLY CONTINUOUS FLOW PRODUCTION PROCESS FOR DIRECTLY PREPARING ORGANIC PEROXIDE FROM ALCOHOL OR ALKANE | SHANGHAI HYBRID CHEM TECH (CN) | 2023-03-29 | — | — | EP | disclosed |
| CN-115626894-A | Lappaconitine derivative with analgesic activity and preparation method and application thereof | 西南交通大学 | 2023-01-20 | — | — | CN | disclosed |
| CN-113105391-B | Lappaconitine derivative with analgesic activity and preparation method and application thereof | 西南交通大学 | 2022-12-16 | — | — | CN | disclosed |
| US-20220144779-A1 | LAPPACONITINE DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION AND APPLICATION THEREOF | SOUTHWEST JIAOTONG UNIVERSITY (CN) | 2022-05-12 | — | — | US | disclosed |
| CN-113105391-A | Lappaconitine derivative with analgesic activity and preparation method and application thereof | 西南交通大学 | 2021-07-13 | — | — | CN | disclosed |
| US-10947189-B2 | Online continuous flow process for the synthesis of organic peroxides using hydrogen peroxide as raw material | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2021-03-16 | — | — | US | disclosed |
| US-4749812-A | N-(3-chloro-4-isopropylphenyl) carboxamide derivative and selective herbicide | MITSUI TOATSU CHEMICALS, INC. (JP) | 1988-06-07 | — | — | US | disclosed |
| US-4742080-A | Therapeutic method for producing bronchodilation by administration of 15-deoxy-16-hydroxy prostaglandin esters | MILES LABORATORIES, INC. (US) | 1988-05-03 | — | — | US | disclosed |
| US-4609650-A | ANTIANDROGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-09-02 | — | — | US | disclosed |
| EP-0124252-A2 | Double ester of 16beta-ethylestran-17beta-ol derivatives | Takeda Chemical Industries, Ltd. (JP) | 1984-11-07 | — | — | EP | disclosed |
| US-4415592-A | ANTISECRETORY AND HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4331688-A | Therapeutic method for inhibiting gastric secretion by administration of 15-deoxy-16-hydroxy prostaglandins | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4275224-A | BRONCHODIALATORS AND ANTI-GASTRIC SECRETION AGENTS | MILES LABORATORIES, INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4132738-A | BRONCHODILATORS, ANTISECRETORY AGENTS | MILES LABORATORIES, INC. (US) | 1979-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947189-B2 | Online continuous flow process for the synthesis of organic peroxides using hydrogen peroxide as raw material | PPOX, HAO2, AOX1 | ALOX5 147/4885APP 918/4885NPC1 2272/4885 |
| US-10919849-B2 | Online continuous flow process for the preparation of organic peroxides direct from alcohols or alkanes | ADH1A, ADH1C, AOX1 | ALOX5 56/4885APP 1371/4885NPC1 1685/4885 |
| US-20200199068-A1 | ONLINE CONTINUOUS FLOW PROCESS FOR THE PREPARATION OF ORGANIC PEROXIDES DIRECT FROM ALCOHOLS OR ALKANES | ADH1A, ADH1C, AOX1 | ALOX5 56/4885APP 1371/4885NPC1 1685/4885 |
| US-11840517-B2 | Lappaconitine derivative with analgesic activity, and preparation and application thereof | LPXN, ACHE, OPRL1 | ALOX5 1542/4885APP 812/4885NPC1 2354/4885 |
| US-20220144779-A1 | LAPPACONITINE DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION AND APPLICATION THEREOF | LPXN, ACHE, OPRL1 | ALOX5 1542/4885APP 812/4885NPC1 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.