SCHEMBL3045651

SCHEMBL3045651

C(/C=C/c1ccccc1)=C\c1ccccc1.O=S(=O)([O-])c1ccccc1-c1ccccc1.[Na+]

nearest known ligand 0.45

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 known ✓ P09917 1/20 0.40
PTGS2 known ✓ P35354 1/20 0.39
MAOB P27338 1/20 0.45
ALDH1A1 P00352 5/20 0.40
TRPA1 O75762 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
CASP1 P29466 2/20 0.38
PTPN1 P18031 1/20 0.38
PTPN6 P29350 1/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL29093047 0.93 PTPN1 (0.43) MAOBLMNAPTGS2CASP1PTPN1
SCHEMBL31276980 0.86 PTGS2 (0.48) ALDH1A1LMNAPTGS2CASP1PTPN1
SCHEMBL29194064 0.86 PTGS2 (0.48) ALDH1A1LMNAPTGS2CASP1PTPN1
SCHEMBL1870051 0.86 PTGS2 (0.48) ALDH1A1LMNAPTGS2CASP1PTPN1
SCHEMBL29991128 0.83 PTPN1 (0.40) MAOBALDH1A1PTGS2CASP1PTPN1
SCHEMBL29213550 0.82 PKLR (0.46) ALDH1A1PTGS2CASP1PTPN1PKLR
SCHEMBL4887779 0.82 PTGS2 (0.48) ALDH1A1LMNAMAPK1PTGS2CASP1
Lithium Ion SCHEMBL3173871 0.82 PTGS2 (0.48) ALDH1A1LMNAMAPK1PTGS2CASP1
Potassium Ion SCHEMBL3400358 0.82 PTGS2 (0.48) ALDH1A1LMNAMAPK1PTGS2CASP1
SCHEMBL4889382 0.82 PTGS2 (0.48) ALDH1A1LMNAMAPK1PTGS2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2021037-B1 PROCESS FOR THE PREPARATION OF A READY-TO-USE DISINFECTANT DU PONT (US) 2010-09-01 EP disclosed
EP-2021037-A1 PROCESS FOR THE PREPARATION OF A READY-TO-USE DISINFECTANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-11 EP disclosed
WO-2007133532-A1 PROCESS FOR THE PREPARATION OF A READY-TO-USE DISINFECTANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-22 WO disclosed
US-20070264356-A1 Process for the preparation of a ready-to-use disinfectant E. I. DU PONT DE NEMOURS AND COMPANY 2007-11-15 US disclosed