Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Naphthalene Trisulfonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.42 |
| ▸ | FGF1 known ✓ | P05230 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene Trisulfonate SCHEMBL29381206 | 1.00 | SIRT1 (0.47) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| Naphthalene Trisulfonate SCHEMBL29496604 | 0.98 | SIRT1 (0.46) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| Naphthalene Trisulfonate SCHEMBL29050218 | 0.98 | SIRT1 (0.46) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| Naphthalene Trisulfonate SCHEMBL3821831 | 0.96 | SIRT1 (0.44) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| SCHEMBL633523 | 0.88 | NSD2 (0.47) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| SCHEMBL5292700 | 0.86 | DUSP5 (0.46) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| Water SCHEMBL29516560 | 0.86 | NSD2 (0.46) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| Water SCHEMBL138857 | 0.86 | NSD2 (0.46) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| SCHEMBL29776130 | 0.85 | DUSP5 (0.43) | SIRT1PRMT1DUSP5PTPN1LMNA | |
| SCHEMBL20538713 | 0.85 | DUSP5 (0.43) | SIRT1PRMT1DUSP5PTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12146184-B2 | Blood glucose measurement reagent, sensor chip, and blood glucose meter set | TERUMO KABUSHIKI KAISHA (JP) | 2024-11-19 | — | — | US | claimed |
| WO-2024104283-A1 | COMPOSITE PLATING SOLUTION, PREPARATION METHOD FOR COMPOSITE COATING, AND ELECTRIC CONTACT MATERIAL. | 温州泰钰新材料科技有限公司 | 2024-05-23 | — | — | WO | claimed |
| US-11719701-B2 | Blood glucose level measuring chip and blood glucose level measuring device set | TERUMO KABUSHIKI KAISHA (JP) | 2023-08-08 | — | — | US | claimed |
| CN-110291185-B | Blood sugar level measurement chip and blood sugar level measurement device set | 泰尔茂株式会社 | 2022-08-09 | — | — | CN | claimed |
| CN-112079450-B | Fluorescent non-phosphorus scale inhibitor | 德蓝水技术股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| US-20210388412-A1 | BLOOD GLUCOSE MEASUREMENT REAGENT, SENSOR CHIP, AND BLOOD GLUCOSE METER SET | TERUMO KABUSHIKI KAISHA (JP) | 2021-12-16 | — | — | US | claimed |
| EP-3578634-B1 | BLOOD SUGAR LEVEL MEASUREMENT CHIP AND BLOOD SUGAR LEVEL MEASUREMENT DEVICE SET | TERUMO CORP (JP) | 2021-12-15 | — | — | EP | claimed |
| US-11130982-B2 | Blood glucose measurement reagent, sensor chip, and blood glucose meter set | TERUMO KABUSHIKI KAISHA (JP) | 2021-09-28 | — | — | US | claimed |
| CN-108368472-B | Blood sugar level measuring reagent, blood sugar level measuring chip, and blood sugar level measuring apparatus set | 泰尔茂株式会社 | 2021-09-21 | — | — | CN | claimed |
| CN-111304708-B9 | Platinum electrodeposition liquid and application thereof | 周生生珠宝金行有限公司 | 2021-02-09 | — | — | CN | claimed |
| US-20060283715-A1 | ZINC-NICKEL ALLOY ELECTROPLATING SYSTEM | PAVCO, INC. | 2006-12-21 | — | — | US | claimed |
| WO-2005113726-A1 | FOULING INHIBITION OF THERMAL TREATMENT OF HEAVY OILS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-12-01 | — | — | WO | claimed |
| WO-2005113727-A2 | INHIBITOR ENHANCED THERMAL UPGRADING OF HEAVY OILS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2005-12-01 | — | — | WO | claimed |
| US-20050258070-A1 | Fouling inhibition of thermal treatment of heavy oils | EXXONMOBIL RESEARCH & ENGINEERING CO. | 2005-11-24 | — | — | US | claimed |
| US-20050258071-A1 | Enhanced thermal upgrading of heavy oil using aromatic polysulfonic acid salts | EXXONMOBIL RESEARCH & ENGINEERING CO. | 2005-11-24 | — | — | US | claimed |
| CN-1516754-A | Mixture for use as brightening agent in electrodeposit solution of silver gold orone of their alloys | 法国梅塔勒科技公司 | 2004-07-28 | — | — | CN | claimed |
| CN-1037470-C | Agent increasing colourfulness and promoting display for diazo blueprint paper | ZHU CHUBIN (CN) | 1998-02-18 | — | — | CN | claimed |
| US-5500668-A | INK JET PRINTING | XEROX CORPORATION (US) | 1996-03-19 | — | — | US | claimed |
| US-5164069-A | PRINTED CIRCUITS | SHIPLEY COMPANY INC. (US) | 1992-11-17 | — | — | US | claimed |
| US-3953304-A | ACETYLENIC DI-PYRIDINIUM COMPOUND | DART INDUSTRIES INC. (US) | 1976-04-27 | — | — | US | claimed |