Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.35 |
| ▸ | DUSP5 | Q16690 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29776130 | 1.00 | DUSP5 (0.43) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| SCHEMBL5292700 | 0.87 | DUSP5 (0.46) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| Naphthalene Trisulfonate SCHEMBL306175 | 0.85 | SIRT1 (0.47) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| Naphthalene Trisulfonate SCHEMBL29381206 | 0.85 | SIRT1 (0.47) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| Naphthalene Trisulfonate SCHEMBL29050218 | 0.84 | SIRT1 (0.46) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| Naphthalene Trisulfonate SCHEMBL29496604 | 0.84 | SIRT1 (0.46) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| SCHEMBL593035 | 0.83 | DUSP5 (0.51) | DUSP5PTPN7PTPN11PTPN1LMNA | |
| Naphthalene Trisulfonate SCHEMBL3821831 | 0.82 | SIRT1 (0.44) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| SCHEMBL305422 | 0.79 | LMNA (0.56) | DUSP5PTPN7PTPN11PTPN1SIRT1 | |
| SCHEMBL8008835 | 0.78 | NT5E (0.47) | DUSP5PTPN7PTPN11PTPN1SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412763-B1 | BLOOD-SUGAR-LEVEL MEASUREMENT REAGENT, BLOOD-SUGAR-LEVEL MEASUREMENT CHIP, AND BLOOD-SUGAR-LEVEL MEASUREMENT DEVICE SET | TERUMO CORP (JP) | 2020-12-23 | — | — | EP | claimed |
| US-12146184-B2 | Blood glucose measurement reagent, sensor chip, and blood glucose meter set | TERUMO KABUSHIKI KAISHA (JP) | 2024-11-19 | — | — | US | disclosed |
| CN-111788472-B | Method, reagent and chip for determining concentration of analyte in biological sample | 泰尔茂株式会社 | 2023-12-15 | — | — | CN | disclosed |
| US-11815448-B2 | Method, reagent, and chip for measuring analyte concentration in specimen | TERUMO KABUSHIKI KAISHA (JP) | 2023-11-14 | — | — | US | disclosed |
| CN-110291185-B | Blood sugar level measurement chip and blood sugar level measurement device set | 泰尔茂株式会社 | 2022-08-09 | — | — | CN | disclosed |
| US-20210388412-A1 | BLOOD GLUCOSE MEASUREMENT REAGENT, SENSOR CHIP, AND BLOOD GLUCOSE METER SET | TERUMO KABUSHIKI KAISHA (JP) | 2021-12-16 | — | — | US | disclosed |
| US-11130982-B2 | Blood glucose measurement reagent, sensor chip, and blood glucose meter set | TERUMO KABUSHIKI KAISHA (JP) | 2021-09-28 | — | — | US | disclosed |
| CN-108368472-B | Blood sugar level measuring reagent, blood sugar level measuring chip, and blood sugar level measuring apparatus set | 泰尔茂株式会社 | 2021-09-21 | — | — | CN | disclosed |
| EP-3412763-B1 | BLOOD-SUGAR-LEVEL MEASUREMENT REAGENT, BLOOD-SUGAR-LEVEL MEASUREMENT CHIP, AND BLOOD-SUGAR-LEVEL MEASUREMENT DEVICE SET | TERUMO CORP (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-20200371020-A1 | METHOD, REAGENT, AND CHIP FOR MEASURING ANALYTE CONCENTRATION IN SPECIMEN | TERUMO KABUSHIKI KAISHA (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3736571-A1 | METHOD, REAGENT, AND CHIP, FOR MEASURING ANALYTE CONCENTRATION IN BIOLOGICAL SAMPLE | TERUMO KABUSHIKI KAISHA (JP) | 2020-11-11 | — | — | EP | disclosed |
| CN-111788472-A | Method, reagent and chip for determining concentration of analyte in biological sample | 泰尔茂株式会社 | 2020-10-16 | — | — | CN | disclosed |
| US-20200165660-A1 | BLOOD GLUCOSE MEASUREMENT REAGENT, SENSOR CHIP, AND BLOOD GLUCOSE METER SET | TERUMO KABUSHIKI KAISHA (JP) | 2020-05-28 | — | — | US | disclosed |
| US-10648015-B2 | Blood glucose measurement reagent, sensor chip, and blood glucose meter set | TERUMO KABUSHIKI KAISHA (JP) | 2020-05-12 | — | — | US | disclosed |
| EP-3412763-A1 | BLOOD-SUGAR-LEVEL MEASUREMENT REAGENT, BLOOD-SUGAR-LEVEL MEASUREMENT CHIP, AND BLOOD-SUGAR-LEVEL MEASUREMENT DEVICE SET | Terumo Kabushiki Kaisha (JP) | 2018-12-12 | — | — | EP | disclosed |
| US-20180305734-A1 | BLOOD GLUCOSE MEASUREMENT REAGENT, SENSOR CHIP, AND BLOOD GLUCOSE METER SET | TERUMO KABUSHIKI KAISHA (JP) | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200371020-A1 | METHOD, REAGENT, AND CHIP FOR MEASURING ANALYTE CONCENTRATION IN SPECIMEN | STUB1, MPO, ALDH1A2 | THRB 3740/4885P2RY2 4575/4885DUSP5 1079/4885 |
| US-11815448-B2 | Method, reagent, and chip for measuring analyte concentration in specimen | STUB1, MPO, ALDH1A2 | THRB 3740/4885P2RY2 4575/4885DUSP5 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.