SCHEMBL3073218

SCHEMBL3073218

CC(C)C(=O)O[C@@H]1[C@@H](OC(=O)C(C)C)[C@H](OP(=O)(O)CC(=O)O)[C@@H](OP(=O)(O)CC(=O)O)[C@@H](OP(=O)(O)CC(=O)O)[C@H]1OC(=O)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3075449 0.83
SCHEMBL3080276 0.78 ITPR3 (0.46)
SCHEMBL3073352 0.78 ITPR3 (0.46)
SCHEMBL3085410 0.78 MEN1 (0.34) MEN1LMNAHPGDTSHRBLM
SCHEMBL3077189 0.77 MEN1 (0.33) MEN1LMNAHPGDTSHRBLM
SCHEMBL3082895 0.77 MEN1 (0.33) MEN1LMNAHPGDTSHRBLM
SCHEMBL3083187 0.75 ALDH1A1 (0.35) MEN1LMNAHPGDTSHRBLM
SCHEMBL3083128 0.73 TLR4 (0.37) KMT2A
SCHEMBL6301309 0.73 ITPR3 (0.54) MEN1LMNAHPGDTSHRBLM
SCHEMBL1149615 0.73 ELANE (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261682-A1 Method and Means for the Treatment of Cachexia BIONERIS AB 2010-10-14 US claimed
US-20160074421-A1 METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT SIRÈN MATTI (FI) 2016-03-17 US disclosed
US-20100261682-A1 Method and Means for the Treatment of Cachexia BIONERIS AB 2010-10-14 US disclosed
US-20090175924-A1 COATED STENT BIONERIS AB (SE) 2009-07-09 US disclosed
EP-1390045-B1 THE USE OF A COMPOUND WITH A NEGATIVELY CHARGED DOMAIN OF PHOSPHOROUS-CONTAINING RADICALS FOR THE TREATMENT OF RESTENOSIS BIONERIS AB (SE) 2008-12-03 EP disclosed
US-20050261756-A1 Coated stent BIONERIS AB (SE) 2005-11-24 US disclosed
US-6949517-B1 Method of treating inflammatory, tissue repair and infectious conditions SIREN MATTI 2005-09-27 US disclosed
US-6632797-B2 Administering to a mammal a cyclic compound (acyclic, carbocyclic or heterocyclic) substituted by at least three vicinal phosphorus containing radicals for treating angiogenesis in tumor conditions SIREN MATTI (FI) 2003-10-14 US disclosed
EP-1216705-A2 The use of growth factor modulation compounds substituted with three vicinal phosphorus containing radical in the manufacture of a medicament for tissue repair PERSTORP AB (SE) 2002-06-26 EP disclosed
US-20020065253-A1 Use of growth factor modulating compounds SIREN MATTI (FI) 2002-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261682-A1 Method and Means for the Treatment of Cachexia PYGM, GYS1, CPT1B MEN1 3255/4885LMNA 846/4885HPGD 433/4885
US-20020065253-A1 Use of growth factor modulating compounds HDGF, PGF, FGF2 MEN1 2889/4885LMNA 4815/4885HPGD 336/4885
US-20160074421-A1 METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT TTPA, LPO, HADHB MEN1 2278/4885LMNA 256/4885HPGD 99/4885
US-20090175924-A1 COATED STENT PHOSPHO1, SOST, PLCB3 MEN1 3551/4885LMNA 1903/4885HPGD 2247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.