SCHEMBL3074545

SCHEMBL3074545

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nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.35
SMPD1 P17405 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6386404 0.85 MPI (0.34) MPI
SCHEMBL7715583 0.83 MPI (0.33) MPI
SCHEMBL1976284 0.83 MPI (0.33) MPI
SCHEMBL7715581 0.83 MPI (0.33) MPI
SCHEMBL9737878 0.83 MPI (0.38) MPI
SCHEMBL18486483 0.83 MPI (0.38) MPI
SCHEMBL3069342 0.83 MPI (0.38) MPI
SCHEMBL3080845 0.83 MPI (0.38) MPI
SCHEMBL3069000 0.83 MPI (0.38) MPI
SCHEMBL9737340 0.82 MPI (0.40) MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261682-A1 Method and Means for the Treatment of Cachexia BIONERIS AB 2010-10-14 US claimed
EP-2187892-A1 METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA Bioneris AB (SE) 2010-05-26 EP claimed
US-20090175924-A1 COATED STENT BIONERIS AB (SE) 2009-07-09 US claimed
WO-2009038533-A1 METHOD AND MEANS FOR THE TREATMENT OF CACHEXIA BIONERIS AB (SE) 2009-03-26 WO claimed
EP-1390045-B1 THE USE OF A COMPOUND WITH A NEGATIVELY CHARGED DOMAIN OF PHOSPHOROUS-CONTAINING RADICALS FOR THE TREATMENT OF RESTENOSIS BIONERIS AB (SE) 2008-12-03 EP claimed
JP-2005537105-A 2005-12-08 JP claimed
US-20050261756-A1 Coated stent BIONERIS AB (SE) 2005-11-24 US claimed
US-20050227946-A1 METHOD OF TREATING INFLAMMATORY, TISSUE REPAIR AND INFECTIOUS CONDITIONS PERSTORP AB (SE) 2005-10-13 US claimed
US-6949517-B1 Method of treating inflammatory, tissue repair and infectious conditions SIREN MATTI 2005-09-27 US claimed
EP-1545643-A1 COATED STENT Bioneris AB, (SE) 2005-06-29 EP claimed
US-20040235799-A1 Use of a compound with a negatively charged domain of radicals for the treatment of restenosis BIONERIS AB (SE) 2004-11-25 US claimed
WO-2004022123-A1 COATED STENT BIONERIS AB (SE) 2004-03-18 WO claimed
EP-0910383-B1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS BIONERIS AB (SE) 2003-10-15 EP claimed
US-6632797-B2 Administering to a mammal a cyclic compound (acyclic, carbocyclic or heterocyclic) substituted by at least three vicinal phosphorus containing radicals for treating angiogenesis in tumor conditions SIREN MATTI (FI) 2003-10-14 US claimed
EP-1216705-A2 The use of growth factor modulation compounds substituted with three vicinal phosphorus containing radical in the manufacture of a medicament for tissue repair PERSTORP AB (SE) 2002-06-26 EP claimed
US-20020065253-A1 Use of growth factor modulating compounds SIREN MATTI (FI) 2002-05-30 US claimed
EP-0910383-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1999-04-28 EP claimed
WO-1997049408-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1997-12-31 WO claimed
US-20160074421-A1 METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT SIRÈN MATTI (FI) 2016-03-17 US disclosed
WO-1997049408-A1 THE USE OF GROWTH FACTOR MODULATING COMPOUNDS PERSTORP AB (SE) 1997-12-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261682-A1 Method and Means for the Treatment of Cachexia PYGM, GYS1, CPT1B MPI 3445/4885SMPD1 3174/4885
US-20020065253-A1 Use of growth factor modulating compounds HDGF, PGF, FGF2 MPI 1461/4885SMPD1 1070/4885
US-20160074421-A1 METHOD FOR THE TREATMENT OF DISEASES CAUSED BY HAEMORRHAGIC VIRUSES AND COMPOUNDS FOR USE IN SAID TREATMENT TTPA, LPO, HADHB MPI 2409/4885SMPD1 2246/4885
US-20040235799-A1 Use of a compound with a negatively charged domain of radicals for the treatment of restenosis PCNA, OPRK1, OGFR MPI 3491/4885SMPD1 2414/4885
US-20090175924-A1 COATED STENT PHOSPHO1, SOST, PLCB3 MPI 1270/4885SMPD1 3221/4885
US-20050227946-A1 METHOD OF TREATING INFLAMMATORY, TISSUE REPAIR AND INFECTIOUS CONDITIONS TNF, TLR2, TPMT MPI 739/4885SMPD1 1166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.