Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 1/20 | 0.45 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | CES2 | O00748 | 4/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.76 |
| ▸ | BLM | P54132 | 3/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.76 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.76 |
| ▸ | EED | O75530 | 5/20 | 0.64 |
| ▸ | SUZ12 | Q15022 | 5/20 | 0.64 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.64 |
| ▸ | IDO1 | P14902 | 6/20 | 0.48 |
| ▸ | TDO2 | P48775 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tanshinone Iia Sulfonic Acid SCHEMBL30094475 | 0.87 | MEN1 (1.00) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iia Sulfonic Acid SCHEMBL28665868 | 0.87 | MEN1 (1.00) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iib SCHEMBL14417728 | 0.78 | EED (1.00) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iib SCHEMBL11945767 | 0.78 | EED (1.00) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Tanshinone Iia Sulfonic Acid SCHEMBL14417738 | 0.77 | MEN1 (0.80) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL14417881 | 0.75 | MEN1 (0.80) | MEN1ALDH1A1KMT2ACES2HPGD | |
| Isotanshinone Iib SCHEMBL30381469 | 0.73 | EED (0.85) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL25752309 | 0.73 | MEN1 (0.75) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL14417741 | 0.69 | MEN1 (0.67) | MEN1ALDH1A1KMT2ACES2HPGD | |
| SCHEMBL28411969 | 0.69 | MEN1 (0.67) | MEN1ALDH1A1KMT2ACES2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912516-A | Tanshinone IIA sodium sulfonate related substance and refining method thereof | 上海上药第一生化药业有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119912517-A | Tanshinone IIB sodium sulfonate derivative and refining method thereof | 上海上药第一生化药业有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119912517-A | Tanshinone IIB sodium sulfonate derivative and refining method thereof | 上海上药第一生化药业有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-117924405-A | Refining method of tanshinone IIA sodium sulfonate | 上海上药第一生化药业有限公司 | 2024-04-26 | — | — | CN | disclosed |