SCHEMBL30869587

SCHEMBL30869587

FC(F)(F)c1cc2c(cc1-c1cccc3[nH]ncc13)Sc1cc(-c3cccc4[nH]ncc34)ccc1N2CCN1CCOCC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 2/20 0.41
KDM1A O60341 5/20 0.39
PIK3CA P42336 10/20 0.38
USP2 O75604 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
WNT1 P04628 1/20 0.36
DYRK1A Q13627 1/20 0.36
METAP2 P50579 1/20 0.36
PIK3CB P42338 2/20 0.36
PIK3CD O00329 2/20 0.36
MTOR P42345 2/20 0.36
PIK3R1 P27986 1/20 0.35
AXL P30530 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30869756 0.90 PIK3CG (0.49) PIK3CGKDM1APIK3CAMETAP2PIK3CB
SCHEMBL30869711 0.83 PRKCQ (0.45) PIK3CGKDM1APIK3CAPIK3CBPIK3CD
SCHEMBL30869729 0.76 PIK3CG (0.48) PIK3CGPIK3CAWNT1DYRK1AMETAP2
SCHEMBL30869650 0.75 PIK3CD (0.47) KDM1APIK3CAPIK3CBPIK3CD
SCHEMBL30869713 0.74 PIK3CA (0.36) PIK3CGKDM1APIK3CAPIK3CDPIK3R1
SCHEMBL32682887 0.73 EGFR (0.52) KDM1APIK3CACLK4DYRK1A
SCHEMBL30869697 0.70 BRAF (0.42) METAP2
SCHEMBL30869717 0.69 PIK3CG (0.41) PIK3CGKDM1APIK3CAMETAP2PIK3CD
SCHEMBL27350370 0.69 ABL1 (0.33)
SCHEMBL32682882 0.68 KDM1A (0.47) KDM1AWNT1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070880-A1 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES, INC. (US) 2026-03-12 US disclosed
EP-4583868-A2 DYNAMIN ACTIVATORS Walden Biosciences, Inc. (US) 2025-07-16 EP disclosed
WO-2024054661-A2 DYNAMIN ACTIVATORS WALDEN BIOSCIENCES (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070880-A1 DYNAMIN ACTIVATORS DNM1, DNM1L, DNM2 PIK3CG 159/4885KDM1A 3264/4885PIK3CA 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.