Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | MPO | P05164 | 5/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29206360 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTRAB9APCSK9 | |
| SCHEMBL30877218 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTRAB9APCSK9 | |
| SCHEMBL2035484 | 0.78 | GPR84 (0.53) | ALDH1A1RAB9ASLC6A4MPOPCSK9 | |
| SCHEMBL30877213 | 0.77 | HTR2A (0.52) | ALDH1A1SLC6A4GPR84NR4A2 | |
| SCHEMBL30053545 | 0.77 | MPO (0.44) | ALDH1A1LMNAHTTRAB9ASLC6A4 | |
| SCHEMBL30909242 | 0.75 | MPO (0.57) | ALDH1A1RAB9ASLC6A4MPOPCSK9 | |
| SCHEMBL2034149 | 0.75 | NR4A2 (0.70) | ALDH1A1LMNAHTTRAB9AMPO | |
| SCHEMBL1559436 | 0.74 | RAB9A (0.49) | RAB9ASLC6A4MPOPCSK9GPR84 | |
| SCHEMBL30877316 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTRAB9AGPR84 | |
| SCHEMBL9506409 | 0.73 | RAB9A (0.55) | RAB9AMPOGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | claimed |
| US-20240286998-A1 | FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | SAINT JOSEPH'S UNIVERSITY | 2024-08-29 | — | — | US | disclosed |
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240286998-A1 | FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | TPH2, TPH1, HNMT | ALDH1A1 2468/4885LMNA 1424/4885HTT 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.