SCHEMBL30978

SCHEMBL30978

N#Cc1c(O)cccc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 5/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
GAA P10253 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
TAS1R2 Q8TE23 1/20 0.38
SOS2 Q07890 1/20 0.37
TRPV4 Q9HBA0 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
EGFR P00533 2/20 0.36
CA2 P00918 2/20 0.36
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2285228 0.83 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL186269 0.83 ALDH1A1 (0.50) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL8811099 0.79 ESR1 (0.41) ALDH1A1KDM4EHPGDHSD17B10MAPT
Cyanide SCHEMBL28871133 0.78 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL7156428 0.77 CES2 (0.39) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL19062287 0.76 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL1285613 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL186554 0.74 KDM4E (0.44) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL30473828 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDHSD17B10MAPT
SCHEMBL28317173 0.73 ALDH1A1 (0.45) ALDH1A1KDM4EHPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111162313-A Polymer electrolyte and lithium ion battery 珠海冠宇电池有限公司 2020-05-15 CN claimed
EP-0606858-B1 Liquid crystal compositions and liquid crystal display devices CHISSO CORP (JP) 2000-04-26 EP claimed
US-5985170-A OF SUPERTWISTED NEMATIC (STN) MODE, CYANOPHENOL, (TRIFLUOROMETHYL)CYANOPHENOL, AND CYANODIFLUOROPHENOL, CONTROLLING A VOLTAGE HOLDING RATIO CHISSO CORPORATION (JP) 1999-11-16 US claimed
US-5723065-A CONDENSED HETEROCYCLE AND AROMATIC AMINE, ALIPHATIC AMINE AND FLUOROCYANOPHENOL CHISSO CORPORATION (JP) 1998-03-03 US claimed
EP-0606858-A1 Liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 1994-07-20 EP claimed
JP-9143139-A None JP disclosed
EP-3750890-B1 ALKOXYBENZO-FIVE-MEMBERED (SIX-MEMBERED) HETEROCYCLIC AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF SHIJIAZHUANG YILING PHARMACEUTICAL CO LTD (CN) 2026-04-01 EP disclosed
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 US disclosed
US-20250257076-A1 SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2025-08-14 US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 US disclosed
US-20250197388-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE EMPRESS THERAPEUTICS, INC. 2025-06-19 US disclosed
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2025-05-13 US disclosed
US-5985170-A OF SUPERTWISTED NEMATIC (STN) MODE, CYANOPHENOL, (TRIFLUOROMETHYL)CYANOPHENOL, AND CYANODIFLUOROPHENOL, CONTROLLING A VOLTAGE HOLDING RATIO CHISSO CORPORATION (JP) 1999-11-16 US disclosed
WO-1999014187-A1 BENZAMIDOXIM DERIVATIVES, INTERMEDIATE PRODUCTS AND METHODS FOR PREPARING AND USING THEM AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-03-25 WO disclosed
US-5723065-A CONDENSED HETEROCYCLE AND AROMATIC AMINE, ALIPHATIC AMINE AND FLUOROCYANOPHENOL CHISSO CORPORATION (JP) 1998-03-03 US disclosed
JP-H09143139-A PRODUCTION OF CYANOFLUOROPHENOL TOHKEM PROD:KK 1997-06-03 JP disclosed
EP-0606858-A1 Liquid crystal compositions and liquid crystal display devices CHISSO CORPORATION (JP) 1994-07-20 EP disclosed
US-5264538-A Cyclic poly(aryl ether) oligomers THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
US-5264520-A Polymerization of cyclic poly(aryl ether) oligomers THE DOW CHEMICAL COMPANY (US) 1993-11-23 US disclosed
EP-0413257-A2 Cyclic poly(aryl ether) oligomers, a process for preparation thereof, and polymerization of cyclic poly (aryl ether) oligomers THE DOW CHEMICAL COMPANY (US) 1991-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B ALDH1A1 1864/4885KDM4E 800/4885HPGD 4289/4885
US-12297209-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 ALDH1A1 621/4885KDM4E 1198/4885HPGD 869/4885
US-20250197388-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE SI, VIP, APC ALDH1A1 3871/4885KDM4E 1497/4885HPGD 523/4885
US-20250257076-A1 SUBSTITUTED PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS cGAS INHIBITORS CGAS, SSB, FPGS ALDH1A1 1529/4885KDM4E 3122/4885HPGD 247/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 ALDH1A1 982/4885KDM4E 4009/4885HPGD 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.