Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989848 | 0.88 | MAPT (0.43) | RXFP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30989973 | 0.88 | RIPK1 (0.44) | RXFP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30989967 | 0.88 | RIPK1 (0.44) | RXFP1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL30989909 | 0.84 | CLK1 (0.48) | MEN1KMT2AALDH1A1MAPK1LMNA | |
| SCHEMBL30989930 | 0.82 | HSP90AA1 (0.52) | RXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL30989921 | 0.82 | RIPK1 (0.45) | MAPTALDH1A1GPBAR1RIPK1PIK3C3 | |
| SCHEMBL30989886 | 0.81 | CLK1 (0.44) | GPBAR1POLBPTGER4RIPK1PIK3C3 | |
| SCHEMBL30989813 | 0.80 | CLK1 (0.43) | GPBAR1POLBPTGER4RIPK1PIK3C3 | |
| SCHEMBL30989898 | 0.79 | GPBAR1 (0.42) | MAPTMEN1KMT2AALDH1A1GPBAR1 | |
| SCHEMBL30989888 | 0.78 | ROCK2 (0.53) | MEN1KMT2AMAPK1POLBPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |