Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31214075 | 0.86 | HCAR2 (0.37) | ASPHTRPM8GLAHPGDEGLN1 | |
| SCHEMBL30401147 | 0.84 | ALDH1A1 (0.42) | ASPHTRPM8GLAHPGDHTT | |
| SCHEMBL23012605 | 0.80 | ASPH (0.46) | ASPHGLAHPGDEGLN1MRGPRX4 | |
| SCHEMBL1106061 | 0.79 | ASPH (0.45) | ASPHGLAHPGDHCAR2KMO | |
| SCHEMBL17047064 | 0.79 | ASPH (0.45) | ASPHGLAHPGDHCAR2KMO | |
| SCHEMBL875231 | 0.76 | HCAR2 (0.42) | ASPHHCAR2KMOLMNAKDM4E | |
| SCHEMBL287761 | 0.75 | LMNA (0.47) | GLAHPGDHCAR2LMNASMN1; SMN2 | |
| SCHEMBL3128651 | 0.75 | L3MBTL1 (0.39) | ASPHTRPM8GLAEGLN1MRGPRX4 | |
| SCHEMBL10328704 | 0.75 | ASPH (0.41) | ASPHMRGPRX4HTTMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7687784 | 0.74 | HCAR2 (0.41) | ASPHHCAR2KMOLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023165957-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | WO | disclosed |
| EP-4238972-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer AG (DE) | 2023-09-06 | — | — | EP | disclosed |
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| CN-103459386-B | N- (1,2, 5-oxadiazol-3-yl) pyridinecarboxamides and their use as herbicides | 拜耳知识产权有限责任公司 | 2016-06-22 | — | — | CN | disclosed |
| US-9035064-B2 | N-(1,2,5-oxadiazol-3-yl)pyridinecarboxamides and use thereof as herbicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| EP-2686316-B1 | N-(1,2,5-OXADIAZOL-3-YL)PYRIDINECARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER IP GMBH (DE) | 2015-04-22 | — | — | EP | disclosed |
| US-20150099766-A1 | Novel halogen-substituted compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-09 | — | — | US | disclosed |
| US-8946234-B2 | Halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-20140066301-A1 | N-(1,2,5-OXADIAZOL-3-YL)PYRIDINECARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-03-06 | — | — | US | disclosed |
| EP-2686316-A1 | N-(1,2,5-OXADIAZOL-3-YL)PYRIDINECARBOXAMIDES AND USE THEREOF AS HERBICIDES | Bayer Intellectual Property GmbH (DE) | 2014-01-22 | — | — | EP | disclosed |
| WO-2012123416-A1 | N-(1,2,5-OXADIAZOL-3-YL)PYRIDINECARBOXAMIDES AND USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2012-09-20 | — | — | WO | disclosed |
| US-20110301181-A1 | halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301181-A1 | halogen-substituted compounds | L3MBTL4, QSOX1, L3MBTL3 | ASPH 4557/4885TRPM8 4484/4885GLA 1236/4885 |
| US-20140066301-A1 | N-(1,2,5-OXADIAZOL-3-YL)PYRIDINECARBOXAMIDES AND USE THEREOF AS HERBICIDES | CBR3, PRDX4, PRDX1 | ASPH 724/4885TRPM8 4359/4885GLA 2765/4885 |
| US-20150099766-A1 | Novel halogen-substituted compounds | L3MBTL4, PRDX4, PRDX1 | ASPH 4493/4885TRPM8 4350/4885GLA 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.