SCHEMBL3134496

SCHEMBL3134496

ClC[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TRPA1 O75762 1/20 0.33
MAPK1 P28482 1/20 0.33
GSK3B P49841 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.33
CALM1 P0DP23 1/20 0.32
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
HTT P42858 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040587 0.97 TRPA1 (0.32) ALDH1A1TRPA1MAPK1GSK3BHIF1A
SCHEMBL10319853 0.86 LMNA (0.42) ALDH1A1TSHRNPC1POLBHTT
SCHEMBL10318708 0.82 ACHE (0.33) TSHR
SCHEMBL10317740 0.82 LTA4H (0.48) TSHR
SCHEMBL10319291 0.82 TP53 (0.50) ALDH1A1TRPA1MAPK1TSHRNPC1
SCHEMBL10318822 0.81 TSHR (0.37) ALDH1A1TSHRNPC1RAB9AKMT2A
SCHEMBL10320597 0.81 ALDH1A1 (0.42) ALDH1A1MAPK1TSHRNPC1HTT
SCHEMBL10319680 0.81 CNR2 (0.36) ALDH1A1NPC1RAB9A
SCHEMBL10318938 0.81 ACHE (0.41) ALDH1A1MAPK1TSHRNPC1HTT
SCHEMBL12815553 0.81 TSHR (0.32) ALDH1A1TSHRPOLBRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4481366-A Process for the preparation of a trifluorovinylsilane, and fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-11-06 US claimed
EP-0119404-A1 Fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-09-26 EP claimed
CN-122071621-A Surface treatment composition 大金工业株式会社 2026-05-22 CN disclosed
EP-4700068-A1 SILANE COMPOUND Daikin Industries, Ltd. (JP) 2026-02-25 EP disclosed
WO-2025075041-A1 SILANE COMPOUND ダイキン工業株式会社 2025-04-10 WO disclosed
WO-2024242181-A1 SILANE COMPOUND ダイキン工業株式会社 2024-11-28 WO disclosed
US-20240309010-A1 METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF MEIJI SEIKA PHARMA CO., LTD. (JP) 2024-09-19 US disclosed
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2024-07-18 US disclosed
EP-4365174-A1 METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF Meiji Seika Pharma Co., Ltd. (JP) 2024-05-08 EP disclosed
CN-117295744-A Method for producing benzoxazole derivative having bicyclic piperazine ring or salt thereof, and method for producing raw material therefor 明治制果药业株式会社 2023-12-26 CN disclosed
US-11664093-B2 Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-05-30 US disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed
US-5608095-A Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents HOECHST MARION ROUSSEL, INC. (US) 1997-03-04 US disclosed
EP-0119404-B1 FLUORINE-CONTAINING POLYMER AND PROCESS FOR ITS PREPARATION SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-04-06 EP disclosed
US-4582841-A ANTITUMOR AND -CARCINOGENIC AGENTS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed
EP-0132231-A2 Substituted thiazolidinyl esters made from inorganic acid amides CIBA-GEIGY AG (CH) 1985-01-23 EP disclosed
EP-0129834-A2 Photo and radiation-sensitive organopolymeric material HITACHI, LTD. (JP) 1985-01-02 EP disclosed
US-4481366-A Process for the preparation of a trifluorovinylsilane, and fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-11-06 US disclosed
EP-0119404-A1 Fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-09-26 EP disclosed
US-4139403-A Dinitroalkyl and fluorodinitroalkyl silicon compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1979-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240309010-A1 METHOD FOR PRODUCING BENZOXAZOLE DERIVATIVE HAVING BICYCLIC PIPERAZINE RING OR SALT THEREOF, AND METHOD FOR PRODUCING MATERIAL THEREOF BAZ2B, JAK2, BRIX1 ALDH1A1 792/4885TRPA1 824/4885MAPK1 968/4885
US-20240238771-A1 SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS HAO2, SCO2, SOD1 ALDH1A1 2963/4885TRPA1 4029/4885MAPK1 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.