Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 9/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409572 | 0.87 | GPR84 (0.49) | GPR84TDO2HTR2AIDO1 | |
| SCHEMBL6409577 | 0.84 | GPR84 (0.46) | GPR84TDO2HTR2AIDO1 | |
| SCHEMBL3144513 | 0.81 | GPR84 (0.46) | GPR84HTR2AIDO1 | |
| SCHEMBL460942 | 0.77 | SLC22A6 (0.51) | GPR84 | |
| SCHEMBL29769232 | 0.77 | SLC22A6 (0.51) | GPR84 | |
| SCHEMBL14527873 | 0.75 | GPR84 (0.53) | GPR84TDO2HTR2AIDO1 | |
| SCHEMBL3144514 | 0.72 | GPR84 (0.46) | GPR84HTR2AIDO1 | |
| SCHEMBL9119246 | 0.72 | SLC22A6 (0.62) | GPR84TDO2HTR2AIDO1 | |
| SCHEMBL1921362 | 0.70 | CSNK2A1 (0.43) | — | |
| Phosphoric Acid SCHEMBL1231445 | 0.69 | GPR84 (0.54) | GPR84TDO2HTR2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090929-B2 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LIMITED (GB) | 2015-07-28 | — | — | US | claimed |
| EP-2186906-B1 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LTD (GB) | 2012-07-25 | — | — | EP | claimed |
| EP-2186906-A2 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LIMITED (GB) | 2010-05-19 | — | — | EP | claimed |
| US-20100120086-A1 | MEDIUM FOR DETECTING AND DIFFERENTIATING VANCOMYCIN-RESISTANT ENTEROCOCCI | OXOID LTD. (GB) | 2010-05-13 | — | — | US | claimed |
| US-9090929-B2 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LIMITED (GB) | 2015-07-28 | — | — | US | disclosed |
| EP-2186906-B1 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LTD (GB) | 2012-07-25 | — | — | EP | disclosed |
| EP-2186906-A2 | Medium for detecting and differentiating vancomycin-resistant enterococci | OXOID LIMITED (GB) | 2010-05-19 | — | — | EP | disclosed |
| US-20100120086-A1 | MEDIUM FOR DETECTING AND DIFFERENTIATING VANCOMYCIN-RESISTANT ENTEROCOCCI | OXOID LTD. (GB) | 2010-05-13 | — | — | US | disclosed |