Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.79 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CCR2 | P41597 | 1/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | CHKA | P35790 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22014103 | 0.98 | SIGMAR1 (0.76) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| Hydrochloric Acid SCHEMBL2235130 | 0.98 | SIGMAR1 (0.76) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL20676124 | 0.98 | SIGMAR1 (0.76) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL5651043 | 0.93 | CXCR4 (0.73) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL6138636 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL276363 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL83548 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| Benzene SCHEMBL27761330 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL152631 | 0.88 | SIGMAR1 (1.00) | SIGMAR1CXCR4MEN1KMT2AHRH3 | |
| SCHEMBL8145866 | 0.86 | SIGMAR1 (0.96) | SIGMAR1CXCR4MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1066188-A | — | — | None | — | — | JP | disclosed |
| US-12018004-B2 | Carbamate compounds and methods of making and using same | H. LUNDBECK A/S (DK) | 2024-06-25 | — | — | US | disclosed |
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2023-10-05 | — | — | US | disclosed |
| US-11530189-B2 | Carbamate compounds and methods of making and using same | H. LUNDBECKA/S (DK) | 2022-12-20 | — | — | US | disclosed |
| CN-110123820-B | Arginase inhibitors and methods of use thereof | 阿斯利康公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-107982266-B | Carbamate compounds and methods of making and using the same | H.隆德贝克有限公司 | 2021-07-30 | — | — | CN | disclosed |
| US-20210188793-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | LUNDBECK LA JOLLA RESEARCH CENTER, INC. | 2021-06-24 | — | — | US | disclosed |
| US-11021453-B2 | Carbamate compounds and methods of making and using same | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200270223-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2020-08-27 | — | — | US | disclosed |
| EP-3698782-A1 | CARBAMATE COMPOUNDS FOR USE IN THERAPY | Lundbeck La Jolla Research Center, Inc. (US) | 2020-08-26 | — | — | EP | disclosed |
| US-20120171116-A1 | Arginase Inhibitors and Methods of Use Thereof | CORRIDOR PHARMACEUTICALS, INC. | 2012-07-05 | — | — | US | disclosed |
| US-20100105694-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ANDRES-GIL JOSE IGNACIO | 2010-04-29 | — | — | US | disclosed |
| US-20100105694-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ANDRES-GIL JOSE IGNACIO | 2010-04-29 | — | — | US | disclosed |
| US-20100105694-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ANDRES-GIL JOSE IGNACIO | 2010-04-29 | — | — | US | disclosed |
| EP-2091942-B1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA NV (BE) | 2010-02-17 | — | — | EP | disclosed |
| EP-2091942-B1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA NV (BE) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008043775-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | JANSSEN PHARMACEUTICA NV (BE) | 2008-04-17 | — | — | WO | disclosed |
| CN-1741810-A | Glycopeptide antibiotic derivatives | LEUVEN K U RES & DEV (BE) | 2006-03-01 | — | — | CN | disclosed |
| US-4876258-A | RIFAMYCIN BACTERICIDE, VIRICIDE | CIBA-GEIGY CORPORATION (US) | 1989-10-24 | — | — | US | disclosed |
| EP-0303571-A1 | Bisphenylyl compounds | CIBA-GEIGY AG (CH) | 1989-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171116-A1 | Arginase Inhibitors and Methods of Use Thereof | ARG1, ARG2, PRMT1 | SIGMAR1 2341/4885CXCR4 2380/4885MEN1 3712/4885 |
| US-11530189-B2 | Carbamate compounds and methods of making and using same | ABHD6, ABHD16A, RABL6 | SIGMAR1 2962/4885CXCR4 4484/4885MEN1 2626/4885 |
| US-11021453-B2 | Carbamate compounds and methods of making and using same | ABHD6, ABHD16A, RABL6 | SIGMAR1 2939/4885CXCR4 4495/4885MEN1 2677/4885 |
| US-20210188793-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | SIGMAR1 2962/4885CXCR4 4484/4885MEN1 2626/4885 |
| US-20200270223-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, NCEH1 | SIGMAR1 2084/4885CXCR4 4080/4885MEN1 2436/4885 |
| US-20100105694-A1 | SUBSTITUTED PYRAZINONE DERIVATIVES FOR USE AS A MEDICINE | ADRA2C, CHRNA5, ADRB2 | SIGMAR1 62/4885CXCR4 2542/4885MEN1 4417/4885 |
| US-20230312499-A1 | CARBAMATE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | SIGMAR1 2962/4885CXCR4 4484/4885MEN1 2626/4885 |
| US-12018004-B2 | Carbamate compounds and methods of making and using same | ABHD6, ABHD16A, RABL6 | SIGMAR1 2962/4885CXCR4 4484/4885MEN1 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.