Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 8/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649296 | 0.91 | HTR2A (0.40) | KDM4EALDH1A1HTR2AHSD11B1SIGMAR1 | |
| SCHEMBL31649065 | 0.85 | TACR1 (0.39) | KDM4EALDH1A1DPP4DPP9HSD11B1 | |
| SCHEMBL31649221 | 0.84 | HSD11B1 (0.40) | KDM4EHSD11B1 | |
| SCHEMBL31649185 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL31649158 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL31649284 | 0.83 | HSD11B1 (0.39) | ALDH1A1DPP4HTR2AHSD11B1SLC6A2 | |
| SCHEMBL31649444 | 0.83 | BCHE (0.41) | OPRM1KDM4EALDH1A1HSD11B1SIGMAR1 | |
| SCHEMBL31649462 | 0.81 | ACHE (0.43) | OPRM1DPP4DPP9DPP7HSD11B1 | |
| SCHEMBL31649151 | 0.81 | ACHE (0.43) | OPRM1DPP4DPP9DPP7HSD11B1 | |
| SCHEMBL31649409 | 0.80 | RORC (0.40) | HSD11B1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |