Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9732830 | 0.98 | KMT2A (0.65) | KMT2AMEN1TDP1CTDSP1CYP1A2 | |
| Bicarbonate SCHEMBL11577700 | 0.87 | MEN1 (0.81) | KMT2AMEN1TDP1CTDSP1MAOA | |
| SCHEMBL6381611 | 0.85 | KMT2A (0.63) | KMT2AMEN1TDP1CTDSP1MAOA | |
| Acetic Acid SCHEMBL4203427 | 0.83 | MEN1 (0.74) | KMT2AMEN1TDP1CTDSP1MAOA | |
| Acetic Acid SCHEMBL8769245 | 0.83 | MEN1 (0.74) | KMT2AMEN1TDP1CTDSP1MAOA | |
| SCHEMBL23607918 | 0.83 | KDM4E (0.59) | KMT2ACYP1A2CYP2C19KDM4ECHRM2 | |
| SCHEMBL11111266 | 0.83 | GAA (0.62) | KMT2AMEN1TDP1CTDSP1GAA | |
| SCHEMBL5300637 | 0.83 | ALDH1A1 (0.59) | KMT2AMEN1CYP2C9CYP2C19CHRM2 | |
| SCHEMBL8851840 | 0.83 | ALDH1A1 (0.64) | KMT2AMEN1TDP1CTDSP1KDM4E | |
| SCHEMBL23124836 | 0.83 | L3MBTL1 (0.50) | KMT2AMEN1TDP1CTDSP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370129-A1 | CARNITINE-PALMITOYL-TRANSFERASE-1 (CPT-1) INHIBITORS FOR USE IN A METHOD OF PREVENTING OR TREATING SEPSIS IN A MAMMALIAN SUBJECT | 2N Pharma ApS (DK) | 2024-05-22 | — | — | EP | disclosed |
| EP-4334313-A1 | DIAZEPANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND USES THEREOF FOR THE AMELIORATION, PREVENTION AND/OR TREATMENT OF MENTAL AND NEUROLOGICAL DISEASES | 2N Pharma ApS (DK) | 2024-03-13 | — | — | EP | disclosed |
| WO-2023285349-A1 | CARNITINE-PALMITOYL-TRANSFERASE-1 (CPT-1) INHIBITORS FOR USE IN A METHOD OF PREVENTING OR TREATING SEPSIS IN A MAMMALIAN SUBJECT | 2N PHARMA APS (DK) | 2023-01-19 | — | — | WO | disclosed |
| US-20220387615-A1 | COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF | DANMARKS TEKNISKE UNIVERSITET (DK) | 2022-12-08 | — | — | US | disclosed |
| EP-3990027-A1 | COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF | Danmarks Tekniske Universitet (DK) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020260597-A1 | COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF | DANMARKS TEKNISKE UNIVERSITET (DK) | 2020-12-30 | — | — | WO | disclosed |
| CN-104876955-B | Arginase inhibitor and its treatment use | 马尔斯公司 | 2018-11-23 | — | — | CN | disclosed |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | REDDY S LAB LIMTED DR (IN) | 2016-06-16 | — | — | US | disclosed |
| EP-3021851-A2 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | Dr. Reddy's Laboratories Ltd. (IN) | 2016-05-25 | — | — | EP | disclosed |
| US-20130261178-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | MISTRY SHAILESH (GB) | 2013-10-03 | — | — | US | disclosed |
| EP-2590937-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | The University Of Nottingham (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004549-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2012-01-12 | — | — | WO | disclosed |
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |
| EP-0611163-B1 | Polymeric biocidal composition and method for making same | SOUTHWEST RES INST (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0611163-A1 | Polymeric biocidal composition and method for making same | SOUTHWEST RESEARCH INSTITUTE (US) | 1994-08-17 | — | — | EP | disclosed |
| US-5173510-A | Anticholesterol agents | AMERICAN CYANAMID COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| US-5053426-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261178-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | NR3C2, NPR3, ADRB3 | KMT2A 4656/4885MEN1 4434/4885TDP1 4370/4885 |
| US-20160168138-A1 | PROCESS FOR THE PREPARATION OF SUVOREXANT AND INTERMEDIATES USEFUL IN THE SYNTHESIS OF SUVOREXANT | KMO, HCRTR2, COMT | KMT2A 163/4885MEN1 505/4885TDP1 4149/4885 |
| US-20220387615-A1 | COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF | ADAM17, ADAM8, ADAM33 | KMT2A 2529/4885MEN1 1111/4885TDP1 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.