SCHEMBL323040

SCHEMBL323040

Brc1cccc(-c2ccc3c4c(cccc24)-c2ccccc2-3)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.47
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
MAPK1 P28482 1/20 0.44
CASP1 P29466 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.41
GABRA1 P14867 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRP O00591 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30509653 1.00 HKDC1 (0.47) HKDC1CRHBPCRHR2KEAP1NFE2L2
SCHEMBL18371181 0.96 HKDC1 (0.45) HKDC1CRHBPCRHR2KEAP1NFE2L2
SCHEMBL20598790 0.90 ALDH1A1 (0.43) HKDC1CRHBPCRHR2KEAP1NFE2L2
SCHEMBL4071420 0.85 MAOB (0.38) HKDC1TSHRALDH1A1HPGDMAPK1
SCHEMBL2163444 0.84 NPC1 (0.48) TSHRALDH1A1HPGDMAPK1GABRA1
SCHEMBL30979958 0.84 NPC1 (0.48) TSHRALDH1A1HPGDMAPK1GABRA1
SCHEMBL19213878 0.83 CYP2A6 (0.46) HKDC1CRHBPCRHR2KEAP1NFE2L2
SCHEMBL16675060 0.82 GABRA1 (0.42) HKDC1TSHRALDH1A1HPGDMAPK1
SCHEMBL16173656 0.82 RAB9A (0.48) HKDC1TSHRALDH1A1HPGDMAPK1
SCHEMBL13098698 0.81 CYP1A2 (0.43) TSHRALDH1A1HPGDCYP1A2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320198-A1 COMPOUND AND APPLICATION THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-10-05 US disclosed
US-20230320198-A1 COMPOUND AND APPLICATION THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-10-05 US disclosed
US-11706981-B2 Organic light emitting device and compounds for use in same IDEMITSU KOSAN CO., LTD. (JP) 2023-07-18 US disclosed
US-11706981-B2 Organic light emitting device and compounds for use in same IDEMITSU KOSAN CO., LTD. (JP) 2023-07-18 US disclosed
CN-110248927-B Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2023-06-30 CN disclosed
US-11588112-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
US-11296282-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-04-05 US disclosed
WO-2021238622-A1 COMPOUND AND APPLICATION THEREOF 广东阿格蕾雅光电材料有限公司 2021-12-02 WO disclosed
EP-3680242-A1 ORGANIC LIGHT EMITTING DEVICE AND COMPOUNDS FOR USE IN SAME Idemitsu Kosan Co., Ltd. (JP) 2020-07-15 EP disclosed
US-20200203632-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-06-25 US disclosed
CN-102265424-A Material for organic electroluminescent element and organic electroluminescent element 2011-11-30 CN disclosed
US-8039127-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US disclosed
US-8039127-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US disclosed
US-8039129-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US disclosed
US-8039129-B2 Organic electroluminescence device and material for organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2011-10-18 US disclosed
EP-2372803-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd. (JP) 2011-10-05 EP disclosed
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100253211-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-07 US disclosed
US-20100253211-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11296282-B2 Organic compound and organic electroluminescence device using the same SLCO4C1, EML4, SLCO2A1 HKDC1 2940/4885CRHBP 4193/4885CRHR2 4824/4885
US-11706981-B2 Organic light emitting device and compounds for use in same SLCO4C1, XPO6, ERCC1 HKDC1 4247/4885CRHBP 3017/4885CRHR2 3129/4885
US-20200203632-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, EML4, SLCO2A1 HKDC1 2940/4885CRHBP 4193/4885CRHR2 4824/4885
US-20100258791-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, LEF1, LIMK1 HKDC1 3805/4885CRHBP 4330/4885CRHR2 4622/4885
US-20230320198-A1 COMPOUND AND APPLICATION THEREOF TRPA1, TRPV5, TRPM5 HKDC1 2846/4885CRHBP 4647/4885CRHR2 4869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.