SCHEMBL3248025

SCHEMBL3248025

CC(=O)Nc1cc(Oc2ccccc2OCC(=O)O)c(Cl)cc1F

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 1/20 0.44
POLB P06746 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GLA P06280 1/20 0.44
PTGDR2 Q9Y5Y4 3/20 0.43
LMNA P02545 4/20 0.42
GAA P10253 1/20 0.42
BRD4 O60885 1/20 0.41
KDM4E B2RXH2 1/20 0.41
FFAR1 O14842 1/20 0.41
CYP2C19 P33261 2/20 0.41
CYP1A2 P05177 1/20 0.41
RAB9A P51151 1/20 0.41
ESRRA P11474 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13397607 0.90 LMNA (0.47) POLBL3MBTL1SMN1; SMN2LMNAGAA
SCHEMBL6245689 0.90 SMN1; SMN2 (0.46) TDP1TSHRPOLBL3MBTL1SMN1; SMN2
SCHEMBL6241694 0.87 L3MBTL1 (0.46) TDP1TSHRPOLBL3MBTL1SMN1; SMN2
SCHEMBL3240280 0.86 L3MBTL1 (0.44) TDP1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL7577594 0.83 ESRRA (0.44) TSHRPOLBL3MBTL1SMN1; SMN2LMNA
SCHEMBL3245165 0.83 ALDH1A1 (0.47) TDP1POLBL3MBTL1SMN1; SMN2GLA
SCHEMBL3251711 0.82 ALDH1A1 (0.40) TDP1TSHRPOLBL3MBTL1SMN1; SMN2
SCHEMBL6244635 0.82 ESRRA (0.44) TSHRPOLBL3MBTL1SMN1; SMN2KDM4E
SCHEMBL19827967 0.81 LMNA (0.35) TDP1TSHRPOLBL3MBTL1SMN1; SMN2
SCHEMBL3246041 0.80 PTGDR2 (0.50) TDP1TSHRPOLBL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1736052-B1 Stem/leaf desiccant SUMITOMO CHEMICAL CO (JP) 2010-04-21 EP disclosed
US-7538072-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-26 US disclosed
EP-1397958-B1 STEM/LEAF DESICCANT SUMITOMO CHEMICAL CO (JP) 2007-01-10 EP disclosed
EP-1736052-A2 Stem/leaf desiccant Sumitomo Chemical Company, Limited (JP) 2006-12-27 EP disclosed
US-20060234865-A1 Using an acylurea compound containing pyrimidine ring;; used before the harvest of crops such as potato, sunflower, soybean, rape, sorghum and the like; methyl [2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]acetate SUMITOMO CHEMICAL COMPANY, LIMITED 2006-10-19 US disclosed
US-7115544-B2 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-03 US disclosed
US-7109148-B2 Stem/leaf desiccant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-19 US disclosed
EP-1106607-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-27 EP disclosed
US-20040152597-A1 Plant growth regulators for cotton hervest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-08-05 US disclosed
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-07-15 US disclosed
EP-1397958-A1 STEAM/LEAF DESSICANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-17 EP disclosed
US-6667413-B2 Aniline derivatives; herbicides; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-23 US disclosed
US-20030130124-A1 Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-10 US disclosed
WO-2002098227-A1 PLANT GROWTH REGULATORS FOR COTTON HERVEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-12 WO disclosed
US-6451740-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20020013466-A1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed
EP-1106607-A2 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152597-A1 Plant growth regulators for cotton hervest GHDC, CBR3, CBR1 TDP1 4332/4885TSHR 2074/4885POLB 3919/4885
US-20060234865-A1 Using an acylurea compound containing pyrimidine ring;; used before the harvest of crops such as potato, sunflower, soybean, rape, sorghum and the like; methyl [2-{2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]phenoxy}phenoxy]acetate CPS1, H1-0, H1-3 TDP1 2524/4885TSHR 2925/4885POLB 2551/4885
US-20030130124-A1 Herbicides CBR3, CBR1, MT-CO1 TDP1 388/4885TSHR 2861/4885POLB 950/4885
US-20020013466-A1 Uracil compounds and use thereof UNG, MRM1, OGG1 TDP1 116/4885TSHR 3504/4885POLB 207/4885
US-20040138063-A1 Using an acylurea compound containing pyrimidine ring CPS1, ACACA, ODC1 TDP1 1991/4885TSHR 3916/4885POLB 2052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.