Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364660 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CYP2A6TDP1TSHRCYP2C9 | |
| SCHEMBL9170505 | 0.81 | TBXAS1 (0.42) | ALDH1A1CYP2A6TDP1TSHRMAOB | |
| SCHEMBL8154332 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP2A6TDP1TSHRMAOB | |
| SCHEMBL398335 | 0.78 | — | — | |
| SCHEMBL4995492 | 0.75 | HSD17B10 (0.48) | CYP2A6MAOBLMNACYP1A2FBP1 | |
| SCHEMBL1301627 | 0.75 | PAM (0.54) | ALDH1A1CYP2C9MAOBPAMLMNA | |
| SCHEMBL1515183 | 0.75 | HSD11B1 (0.40) | ALDH1A1TSHRRECQLMAPTFBP1 | |
| SCHEMBL6650732 | 0.75 | JUN (0.40) | ALDH1A1CYP2C9CYP3A4LMNAHDAC1 | |
| SCHEMBL1301624 | 0.75 | PAM (0.54) | ALDH1A1CYP2C9MAOBPAMLMNA | |
| SCHEMBL4171733 | 0.75 | PAM (0.54) | ALDH1A1CYP2C9MAOBPAMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075124-B | Alpha, omega-functionalized polyoxyalkylene-siloxane polymers and copolymers prepared therefrom | 莫门蒂夫性能材料股份有限公司 | 2020-10-23 | — | — | CN | claimed |
| EP-3194472-B1 | FUNCTIONALIZED POLYOXYALKYLENE-SILOXANE POLYMERS AND COPOLYMERS MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2018-07-11 | — | — | EP | claimed |
| CN-108218785-A | A kind of secondary cell ionic liquid and synthetic method and application | 中国科学院大连化学物理研究所 | 2018-06-29 | — | — | CN | claimed |
| US-9992997-B2 | Composition comprising bromadiolone, rodenticide bait, and method for controlling target rodent pests | LIPHATECH (FR) | 2018-06-12 | — | — | US | claimed |
| CN-105797770-B | (S) the thiourea modified Cr Anderson types heteropolyacid catalyst of 1 (phenylpropyl of 3 hydroxyl 1), preparation method and applications | 上海应用技术学院 | 2018-03-30 | — | — | CN | claimed |
| CN-105665019-B | (S) the thiourea modified Mn Anderson types heteropolyacid catalyst of 1 (phenylpropyl of 3 hydroxyl 1), preparation method and applications | 上海应用技术学院 | 2018-03-02 | — | — | CN | claimed |
| EP-3194472-A1 | FUNCTIONALIZED POLYOXYALKYLENE-SILOXANE POLYMERS AND COPOLYMERS MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2017-07-26 | — | — | EP | claimed |
| US-20170118982-A1 | COMPOSITION COMPRISING BROMADIOLONE, RODENTICIDE BAIT, AND METHOD FOR CONTROLLING TARGET RODENT PESTS | VETAGRO SUP (FR) | 2017-05-04 | — | — | US | claimed |
| CN-106513041-A | (S)-1-(3-hydroxy-1-phenylpropyl)thiourea modified Al-Anderson type heteropolyacid catalyst, preparation method and application thereof | 上海应用技术大学 | 2017-03-22 | — | — | CN | claimed |
| CN-106475141-A | (S) the unilateral Fe Anderson type heteropolyacid catalyst modified of 1 (3 hydroxyl 1 phenylpropyl) thiourea, preparation method and applications | 上海应用技术大学 | 2017-03-08 | — | — | CN | claimed |
| CN-1646460-A | 2- (2, 6-dichlorophenyl) -diarylimidazoles | HOFFMANN LA ROCHE (CH) | 2005-07-27 | — | — | CN | claimed |
| WO-2005040153-A1 | NOVEL TRIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | claimed |
| US-20050085473-A1 | Novel triarylimidazoles | HOFFMANN-LA ROCHE INC. | 2005-04-21 | — | — | US | claimed |
| EP-1499577-A1 | 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-26 | — | — | EP | claimed |
| US-6790852-B2 | HETEROCYCLIC NITROGEN COMPOUNDS SUCH AS 2-(2,6-DICHLOROPHENYL) -4-(3-BROMOPHENYL)-5-(2-(3- HYDROXYPROPYLAMINO)PYRIMIDIN-4-YL) -N-H-IMIDAZOLE, USED AS TYROSINE KINASE INHIBITORS; ANTICARCINOGENIC OR ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. | 2004-09-14 | — | — | US | claimed |
| CN-1494541-A | heterocyclic inhibitors of ERK2 and uses thereof | ��̩��˹ҩ��ɷ�����˾ | 2004-05-05 | — | — | CN | claimed |
| US-20030199691-A1 | 2-(2,6-dichlorophenyl)-diarylimidazoles | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-23 | — | — | US | claimed |
| WO-2003087026-A1 | 2-(2,6-DICHLOROPHENYL)-DIARYLIMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-23 | — | — | WO | claimed |
| US-20020103111-A1 | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-01 | — | — | US | claimed |
| US-4374734-A | WITH A POLYOL AND/OR QUATERNARY AMMONIUM COMPOUND | CITIES SERVICE CO. (US) | 1983-02-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085473-A1 | Novel triarylimidazoles | AURKAIP1, GLS2, GOT2 | ALDH1A1 409/4885CYP2A6 752/4885TDP1 2193/4885 |
| US-20020103111-A1 | Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor | VCAM1, ICAM1, SELPLG | ALDH1A1 1850/4885CYP2A6 4787/4885TDP1 3415/4885 |
| US-20030199691-A1 | 2-(2,6-dichlorophenyl)-diarylimidazoles | CYP2D6, CYP2F1, CYP1A2 | ALDH1A1 115/4885CYP2A6 70/4885TDP1 2263/4885 |
| US-20170118982-A1 | COMPOSITION COMPRISING BROMADIOLONE, RODENTICIDE BAIT, AND METHOD FOR CONTROLLING TARGET RODENT PESTS | HSD17B7, CYP17A1, HSD17B1 | ALDH1A1 1697/4885CYP2A6 169/4885TDP1 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.