Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | USP2 | O75604 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264375 | 0.89 | CASP3 (0.55) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL3263396 | 0.86 | CASP3 (0.65) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL13930934 | 0.85 | RAB9A (0.59) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL13930942 | 0.85 | CASP3 (0.63) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL3266298 | 0.84 | RAB9A (0.56) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL4257823 | 0.82 | RAB9A (0.64) | HSD17B10MAPTKDM4EESR1RAB9A | |
| SCHEMBL3261588 | 0.77 | CASP3 (1.00) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL3262950 | 0.76 | ALOX15 (0.43) | CASP3HSD17B10MAPTKDM4EESR1 | |
| SCHEMBL4594163 | 0.76 | CASP3 (0.64) | CASP3HSD17B10MAPTRAB9ANPC1 | |
| SCHEMBL4252206 | 0.76 | CASP3 (0.55) | CASP3HSD17B10MAPTKDM4EESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111970925-A | Aqueous nematicidal compositions comprising dispersants to inhibit crystal growth | 孟山都技术有限公司 | 2020-11-20 | — | — | CN | claimed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | claimed |
| US-20200107548-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2020-04-09 | — | — | US | claimed |
| US-20200054013-A1 | SEED TREATMENT COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2020-02-20 | — | — | US | claimed |
| CN-110547297-A | Aqueous nematicidal suspension concentrate compositions | MONSANTO TECHNOLOGY LLC | 2019-12-10 | — | — | CN | claimed |
| US-10499645-B2 | Nematicidal aqueous suspension concentrate compositions | MONSANTO TECHNOLOGY, LLC (US) | 2019-12-10 | — | — | US | claimed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | claimed |
| WO-2019183454-A1 | AQUEOUS NEMATICIDAL COMPOSITIONS CONTAINING DISPERSANTS TO INHIBIT CRYSTAL GROWTH | MONSANTO TECHNOLOGY LLC (US) | 2019-09-26 | — | — | WO | claimed |
| US-20190208785-A1 | Composition and Methods for Reducing Nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-07-11 | — | — | US | claimed |
| US-20190090487-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2019-03-28 | — | — | US | claimed |
| WO-2017106715-A1 | COMPOSITION AND METHODS FOR REDUCING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2017-06-22 | — | — | WO | claimed |
| US-9420788-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2016-08-23 | — | — | US | claimed |
| EP-2958431-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | Monsanto Technology LLC (US) | 2015-12-30 | — | — | EP | claimed |
| US-20150342189-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2015-12-03 | — | — | US | claimed |
| EP-2947080-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Monsanto Technology LLC (US) | 2015-11-25 | — | — | EP | claimed |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-06-04 | — | — | US | claimed |
| EP-2184989-B1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2015-05-06 | — | — | EP | claimed |
| CN-104054719-A | Compositions And Methods For Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2014-09-24 | — | — | CN | claimed |
| WO-2014089219-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | MONSANTO TECHNOLOGY LLC (US) | 2014-06-12 | — | — | WO | claimed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054013-A1 | SEED TREATMENT COMPOSITIONS | GYS2, GYS1, SCD5 | CASP3 517/4885HSD17B10 797/4885MAPT 1130/4885 |
| US-20190090487-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | ATL3, NOP2, ACHE | CASP3 11/4885HSD17B10 2766/4885MAPT 3730/4885 |
| US-20200107548-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | ATL3, NOP2, ACHE | CASP3 11/4885HSD17B10 2766/4885MAPT 3730/4885 |
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | CASP3 477/4885HSD17B10 2408/4885MAPT 2961/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885HSD17B10 2408/4885MAPT 2961/4885 |
| US-20150342189-A1 | NEMATICIDAL AQUEOUS SUSPENSION CONCENTRATE COMPOSITIONS | ATL3, MASTL, SPOUT1 | CASP3 134/4885HSD17B10 2491/4885MAPT 1300/4885 |
| US-20150150258-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885HSD17B10 2408/4885MAPT 2961/4885 |
| US-20190208785-A1 | Composition and Methods for Reducing Nematodes | RPL41, SPOUT1, MASTL | CASP3 1319/4885HSD17B10 3310/4885MAPT 2210/4885 |
| US-10499645-B2 | Nematicidal aqueous suspension concentrate compositions | ATL3, NOP2, ACHE | CASP3 11/4885HSD17B10 2766/4885MAPT 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.