Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850247 | 0.91 | ADRB2 (0.44) | ADRB2ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL328560 | 0.91 | MMP3 (0.44) | MMP3MMP1MMP13MMP9ADAM17 | |
| SCHEMBL6863812 | 0.90 | MMP3 (0.52) | MMP3AHCYMMP1MMP13MMP9 | |
| SCHEMBL328555 | 0.88 | MMP3 (0.53) | MMP3ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL328401 | 0.88 | ADRB2 (0.43) | ADRB2MMP3ALDH1A1KMT2ALMNA | |
| SCHEMBL6850180 | 0.82 | MMP9 (0.40) | MMP3ALDH1A1MMP1MMP13MMP9 | |
| SCHEMBL328556 | 0.81 | MMP3 (0.40) | MMP3KMT2AMEN1MAPTAHCY | |
| SCHEMBL6865124 | 0.80 | MMP3 (0.40) | MMP3MMP1MMP13MMP9ADAM17 | |
| SCHEMBL328388 | 0.80 | MMP3 (0.43) | MMP3TSHRPOLBMMP1MMP13 | |
| SCHEMBL328649 | 0.80 | MMP1 (0.44) | MMP3KMT2AMMP1MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |