SCHEMBL331133

SCHEMBL331133

C=C(C)C(=O)SCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 8/20 0.47
NOS3 P29474 1/20 0.47
NOS1 P29475 1/20 0.47
NOS2 P35228 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
GAA P10253 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 3/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713087 0.90 NOS1 (0.41) IDO1NOS3NOS1NOS2TDP1
SCHEMBL1801901 0.87 SLC11A2 (0.47) IDO1NOS3NOS1NOS2TDP1
SCHEMBL4860565 0.84 CYP2C19 (0.53) IDO1CYP2C19ALDH1A1LMNA
SCHEMBL7277542 0.84 IDO1 (0.50) IDO1NOS3NOS1NOS2TDP1
SCHEMBL1412747 0.83 ALDH1A1 (0.50) IDO1NOS1ALDH1A1HDAC3HDAC4
SCHEMBL1802036 0.82 ALDH1A1 (0.35) IDO1TDP1GAATAAR1L3MBTL1
SCHEMBL27472188 0.81 NOS1 (0.31) IDO1NOS3NOS1NOS2TDP1
SCHEMBL26192578 0.80 ACACB (0.38) ALDH1A1
SCHEMBL42484 0.79 IDO1 (0.54) IDO1NOS3NOS1NOS2TDP1
SCHEMBL28340394 0.79 IDO1 (0.54) IDO1NOS3NOS1NOS2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6022496-A Chromene compound TOKUYAMA CORPORATION (JP) 2000-02-08 US claimed
JP-1115910-A None JP disclosed
JP-4304217-A None JP disclosed
CN-122037193-A Cured product, optical element, optical device, and imaging device 佳能株式会社 2026-05-15 CN disclosed
US-20260110823-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND CANON KK (JP) 2026-04-23 US disclosed
US-12595408-B2 Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses TOKUYAMA CORPORATION (JP) 2026-04-07 US disclosed
EP-4692071-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
EP-4692072-A1 PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
US-12529822-B2 Optical element, optical apparatus, imaging apparatus, and compound CANON KABUSHIKI KAISHA (JP) 2026-01-20 US disclosed
US-12479976-B2 Cured product, optical element, optical apparatus, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2025-11-25 US disclosed
EP-0629626-A2 Cyclopropyl-substituted spiro-photochromic compounds TOKUYAMA CORPORATION (JP) 1994-12-21 EP disclosed
EP-0609061-A2 Polymerizable composition, polymer, organic glass and ophthalmic lens TOKUYAMA CORPORATION (JP) 1994-08-03 EP disclosed
US-5246989-A PHOTOCHROMIC COMPOUND, COMPOSITION AND USE THEREOF TOKUYAMA SODA KABISHIKI KAISHA (JP) 1993-09-21 US disclosed
US-5214116-A Acrylic polymers with thioester group, lenses, optical fibers, optical recording media TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1993-05-25 US disclosed
JP-H04304217-A POLYMERIZABLE COMPOSITION TOKUYAMA SODA CO LTD 1992-10-27 JP disclosed
EP-0449669-A1 Photochromic compound, composition and use thereof TOKUYAMA CORPORATION (JP) 1991-10-02 EP disclosed
EP-0382477-A1 Resin having a high refractive index TOKUYAMA CORPORATION (JP) 1990-08-16 EP disclosed
US-4931521-A Optical materials composed of resin from thioacrylat esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-06-05 US disclosed
JP-H01115910-A PRODUCTION OF RESIN WITH HIGH REFRACTIVE INDEX NIPPON SHOKUBAI KAGAKU KOGYO CO LTD 1989-05-09 JP disclosed
EP-0273710-A2 Resin having high refractive index, process for producing said resin and optical materials composed of said resin Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1988-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260110823-A1 OPTICAL ELEMENT, OPTICAL APPARATUS, IMAGING APPARATUS, AND COMPOUND RAD51, PIEZO1, ZYX IDO1 3236/4885NOS3 1098/4885NOS1 1135/4885
US-12595408-B2 Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses CRYAA, CRYZ, CRY2 IDO1 1204/4885NOS3 1924/4885NOS1 1546/4885
US-12529822-B2 Optical element, optical apparatus, imaging apparatus, and compound RAD51, SEM1, PSMA3 IDO1 3317/4885NOS3 673/4885NOS1 1231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.