SCHEMBL33523

SCHEMBL33523

C=C(C)C(=O)OCc1cc(C(=O)O)c(C(=O)O)cc1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 3/20 0.38
THRB P10828 1/20 0.36
ALDH1A1 P00352 6/20 0.34
KDM4E B2RXH2 2/20 0.33
MAPT P10636 1/20 0.32
CFD P00746 2/20 0.31
ELANE P08246 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
PKM P14618 1/20 0.30
MRGPRX4 Q96LA9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33455 0.84 THRB (0.45) POLBAPEX1HTTTDP1TSHR
SCHEMBL2193856 0.81 TDP1 (0.48) POLBAPEX1HTTTDP1TSHR
SCHEMBL2059843 0.81 CA2 (0.36) POLBAPEX1HTTTDP1TSHR
SCHEMBL11519975 0.80 POLB (0.50) POLBAPEX1HTTTDP1TSHR
SCHEMBL14944765 0.80 TSHR (0.47) POLBAPEX1HTTTDP1TSHR
SCHEMBL7077409 0.79 HTT (0.48) POLBAPEX1HTTTDP1TSHR
Pyromellitic Acid SCHEMBL17272685 0.78 POLB (0.47) POLBAPEX1HTTTDP1TSHR
SCHEMBL1556947 0.77 THRB (0.47) POLBAPEX1HTTTDP1TSHR
SCHEMBL4087259 0.77 THRB (0.47) POLBAPEX1HTTTDP1TSHR
SCHEMBL7080186 0.77 THRB (0.47) POLBAPEX1HTTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP claimed
US-8664294-B2 Self etch all purpose dental cement composition and method of use thereof PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2014-03-04 US claimed
US-20110171608-A1 SELF ETCH ALL PURPOSE DENTAL CEMENT COMPOSITION AND METHOD OF USE THEREOF PENTRON CLINICAL TECHNOLOGIES, L.L.C. (US) 2011-07-14 US claimed
US-7906564-B2 Self etch all purpose dental cement composition, method of manufacture, and method of use thereof PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2011-03-15 US claimed
EP-1986588-A2 SELF ETCH ALL PURPOSE DENTAL COMPOSITION Pentron Clinical Technologies, LLC (US) 2008-11-05 EP claimed
US-20080242761-A1 One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable JIA WEITAO 2008-10-02 US claimed
EP-1973587-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS Allaccem, Inc. (US) 2008-10-01 EP claimed
US-7304096-B2 Highly functional dental adhesive composition KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY AND DENTKIST, INC. (KR) 2007-12-04 US claimed
WO-2007100569-A2 SELF ETCH ALL PURPOSE DENTAL COMPOSITION PENTRON CLINICAL TECHNOLOGIES LLC (US) 2007-09-07 WO claimed
US-20070197683-A1 SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF PENTRON CLINICAL TECHNOLOGIES, INC (US) 2007-08-23 US claimed
US-20070197682-A1 Self etch all purpose dental cement composition, method of manufacture, and method of use thereof PENTRON CORPORATION 2007-08-23 US claimed
WO-2007070801-A2 METHODS AND SYSTEMS FOR PREPARING ANTIMICROBIAL FILMS AND COATINGS ALLACCEM, INC. (US) 2007-06-21 WO claimed
US-7226960-B2 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2007-06-05 US claimed
US-7115674-B2 Dental self-curing resin cement compositions DENTKIST, INC. (KR) 2006-10-03 US claimed
US-20050277706-A1 Highly functional dental adhesive composition KOREAN INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-12-15 US claimed
US-20050049326-A1 Dental self-curing resin cement compositions DENTKIST, INC. (KR) 2005-03-03 US claimed
US-20040176496-A1 Light-curing dental adhesive compositions DENTKIST, INC. (KR) 2004-09-09 US claimed
US-20030207960-A1 Self-etching primer adhesive and method of use therefor PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-06 US claimed
US-6326417-B1 CONTAINING SALICYLIC ACID COMPOUND AS MICROBIOCIDES JENERIC/PENTRON INCORPORATED 2001-12-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110171608-A1 SELF ETCH ALL PURPOSE DENTAL CEMENT COMPOSITION AND METHOD OF USE THEREOF FHIT, ASPH, ACR POLB 1010/4885APEX1 786/4885HTT 314/4885
US-20070197682-A1 Self etch all purpose dental cement composition, method of manufacture, and method of use thereof FHIT, COPE, ASH2L POLB 1344/4885APEX1 579/4885HTT 2462/4885
US-20050277706-A1 Highly functional dental adhesive composition CD44, HBG2, HBG1 POLB 234/4885APEX1 1128/4885HTT 911/4885
US-20040176496-A1 Light-curing dental adhesive compositions HBG2, GRIN2A, HBG1 POLB 1017/4885APEX1 961/4885HTT 1497/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS POLB 1257/4885APEX1 166/4885HTT 582/4885
US-20070197683-A1 SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF CAD, FHIT, ACR POLB 1024/4885APEX1 428/4885HTT 1923/4885
US-20080242761-A1 One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable CAD, TAS2R42, ACR POLB 1285/4885APEX1 198/4885HTT 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.