Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356653 | 0.90 | LMNA (0.42) | MAPTACHECYP1A2LMNASIRT2 | |
| SCHEMBL13537606 | 0.80 | MEN1 (0.32) | CYP1A2ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL3349648 | 0.77 | ACHE (0.41) | MAPTACHECYP1A2LMNASIRT2 | |
| SCHEMBL3355907 | 0.76 | ACHE (0.39) | MAPTACHESIRT6HIF1APKM | |
| SCHEMBL3352228 | 0.74 | HTR7 (0.44) | MAPTACHESIRT2SIRT6HIF1A | |
| SCHEMBL3355435 | 0.70 | ALDH1A1 (0.42) | MAPTACHELMNASIRT6HIF1A | |
| SCHEMBL3357241 | 0.70 | ACHE (0.41) | MAPTACHELMNASIRT6HIF1A | |
| SCHEMBL3354484 | 0.70 | ALDH1A1 (0.41) | MAPTACHELMNASIRT6HIF1A | |
| SCHEMBL3352685 | 0.69 | MAPT (0.47) | MAPTACHELMNASIRT6HIF1A | |
| SCHEMBL13537330 | 0.69 | ALDH1A1 (0.33) | CYP1A2LMNAALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |