Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354484 | 0.78 | ALDH1A1 (0.41) | ACHEALDH1A1POLBSIRT6SMN1; SMN2 | |
| SCHEMBL3356653 | 0.78 | LMNA (0.42) | ACHEALDH1A1SIRT6SMN1; SMN2SIRT2 | |
| SCHEMBL3348558 | 0.77 | MAPT (0.39) | ACHEALDH1A1SIRT6SMN1; SMN2SIRT2 | |
| SCHEMBL13537372 | 0.75 | POLB (0.38) | POLBSMN1; SMN2LMNA | |
| SCHEMBL3352228 | 0.75 | HTR7 (0.44) | ACHEALDH1A1SIRT6SIRT2HIF1A | |
| SCHEMBL3357241 | 0.73 | ACHE (0.41) | ACHEALDH1A1SIRT6HIF1AMAPT | |
| SCHEMBL3354823 | 0.73 | LMNA (0.43) | ACHEALDH1A1SIRT6SMN1; SMN2HIF1A | |
| SCHEMBL3355435 | 0.71 | ALDH1A1 (0.42) | ACHEALDH1A1SIRT6SMN1; SMN2HIF1A | |
| SCHEMBL3353280 | 0.71 | HTR7 (0.53) | ACHESIRT6HIF1AMAPTPKM | |
| SCHEMBL3354325 | 0.71 | AVPR1A (0.43) | ACHEALDH1A1POLBSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |