Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595063 | 0.92 | PLAU (0.58) | LTA4HUSP2TP53CES2CES1 | |
| SCHEMBL631022 | 0.85 | LTA4H (0.57) | LTA4HUSP2TP53CES2CES1 | |
| SCHEMBL27773350 | 0.82 | CACNA1B (0.50) | LTA4HUSP2TP53NPC1KDM4E | |
| SCHEMBL28366589 | 0.81 | LTA4H (0.53) | LTA4HUSP2TP53CES2CES1 | |
| SCHEMBL6581234 | 0.81 | LTA4H (0.53) | LTA4HUSP2TP53CES2CES1 | |
| SCHEMBL571063 | 0.81 | USP2 (0.69) | USP2TP53CES2CES1NPC1 | |
| SCHEMBL10603224 | 0.80 | USP2 (0.54) | USP2TP53CES2CES1NPC1 | |
| SCHEMBL28303440 | 0.79 | SMN1; SMN2 (0.84) | LTA4HUSP2TP53CES2CES1 | |
| SCHEMBL127185 | 0.79 | CES1 (0.52) | CES2CES1ALDH1A1MAPTCTBP2 | |
| SCHEMBL29271945 | 0.78 | L3MBTL1 (0.50) | CES2CES1NPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 606 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104769006-B | Regioregular copolymers and process for their preparation | 英派尔科技开发有限公司 | 2017-03-08 | — | — | CN | claimed |
| US-8148423-B2 | Fluorophore compounds | VERSITECH LIMITED (CN) | 2012-04-03 | — | — | US | claimed |
| US-20090253143-A1 | FLUOROPHORE COMPOUNDS | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | US | claimed |
| WO-2009121244-A1 | FLUOROPHORE COMPOUNDS | VERSITECH LIMITED (CN) | 2009-10-08 | — | — | WO | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| US-3953436-A | 3,4-Dicarboxycephalosporins and derivatives | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| US-20240209018-A1 | UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS | GENSCRIPT USA INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208955-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | RESEARCH TRIANGLE INSTITUTE | 2024-06-27 | — | — | US | disclosed |
| US-20240140984-A1 | BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARM INC (US) | 2024-05-02 | — | — | US | disclosed |
| US-11958879-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| EP-4347110-A1 | ELECTROGRAFTED FILMS FOR DNA SYNTHESIS | Genscript USA Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| US-11952389-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-11944687-B2 | Carbohydrate conjugate RNA agents and process for their preparation | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| US-20010049367-A1 | Cyclic and bicyclic diamino histamine-3 receptor antagonists | ABBVIE INC. | 2001-12-06 | — | — | US | disclosed |
| WO-2001077134-A2 | PROCESS FOR THE PREPARATION OF 6-O-PROPARGYL ERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 2001-10-18 | — | — | WO | disclosed |
| US-6277868-B1 | BACTERICIDES; SKIN DISORDERS | ABBOTT LABORATORIES | 2001-08-21 | — | — | US | disclosed |
| US-5057512-A | Bactericides | Uclaf, Roussel (FR) | 1991-10-15 | — | — | US | disclosed |
| US-4900728-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |
| US-4725591-A | USED WITH AMINO ACID DERIVATIVE ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010049367-A1 | Cyclic and bicyclic diamino histamine-3 receptor antagonists | HRH4, HRH2, HRH3 | LTA4H 436/4885USP2 3879/4885TP53 4836/4885 |
| US-11958879-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | GPBAR1, NR1H4, SLC10A1 | LTA4H 996/4885USP2 4282/4885TP53 3670/4885 |
| US-20090253143-A1 | FLUOROPHORE COMPOUNDS | FUCA1, DNA2, LRAT | LTA4H 2187/4885USP2 3282/4885TP53 2203/4885 |
| US-11952389-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | LTA4H 891/4885USP2 4534/4885TP53 4857/4885 |
| US-20240208955-A1 | SMALL MOLECULE ANTAGONISTS FOR THE RELAXIN-3/RXFP3 SYSTEM | RXFP3, RXFP1, RXFP4 | LTA4H 3420/4885USP2 3289/4885TP53 4821/4885 |
| US-20240209018-A1 | UNIVERSAL LINKER REAGENTS FOR DNA SYNTHESIS | RNGTT, DTYMK, UNG | LTA4H 2451/4885USP2 1362/4885TP53 1768/4885 |
| US-20240140984-A1 | BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF | GPBAR1, NR1H4, SLC10A1 | LTA4H 870/4885USP2 4107/4885TP53 4622/4885 |
| US-11944687-B2 | Carbohydrate conjugate RNA agents and process for their preparation | RNASE1, IGF2BP1, IGF2BP2 | LTA4H 4810/4885USP2 2094/4885TP53 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.