Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | MME | P08473 | 1/20 | 0.61 |
| ▸ | ECE1 | P42892 | 1/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475275 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL10954164 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL19384712 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL8177898 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL10954146 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL7421757 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL8181468 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL29453235 | 1.00 | CTSK (0.62) | CTSKMMEECE1CAPN1CTSL | |
| Isopropylamine SCHEMBL11518925 | 0.96 | CTSK (0.58) | CTSKMMEECE1CAPN1CTSL | |
| SCHEMBL856196 | 0.94 | CTSK (0.61) | CTSKMMEECE1CAPN1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279550-B2 | Irreversible cysteine protease inhibitors of legumain | PROBIODRUG AG (DE) | 2007-10-09 | — | — | US | claimed |
| US-20060178315-A1 | Irreversible cysteine protease inhibitors of legumain | PROBIODRUG AG | 2006-08-10 | — | — | US | claimed |
| EP-0783489-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | claimed |
| WO-1996010014-A1 | ALDEHYDE DERIVATIVES AS UPSTEINE PROTEASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-04 | — | — | WO | claimed |
| EP-4725560-A2 | ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS | Bayer Pharma Aktiengesellschaft (DE) | 2026-04-15 | — | — | EP | disclosed |
| EP-4703369-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY USING TEMPORARILY PROTECTED AMINO ACIDS AS AMINE COMPONENTS | GUANGZHOU MEDICAL UNIVERSITY (CN) | 2026-03-04 | — | — | EP | disclosed |
| US-20260008808-A1 | Method for Synthesizing Amide and/or Polypeptide Using Unprotected Amino Acid as Ammonia Component | UNIV GUANGZHOU MEDICAL (CN) | 2026-01-08 | — | — | US | disclosed |
| US-20260001906-A1 | Method for Synthesizing Amide and/or Polypeptide Using Temporary Protected Amino Acid as Ammonia Component | UNIV GUANGZHOU MEDICAL (CN) | 2026-01-01 | — | — | US | disclosed |
| EP-4642484-A1 | TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE | Hangzhou Seehe Biotechnology Co., Ltd (CN) | 2025-11-05 | — | — | EP | disclosed |
| EP-4574834-A1 | METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE WITH UNPROTECTED AMINO ACID AS AMINE COMPONENT | GUANGZHOU MEDICAL UNIVERSITY (CN) | 2025-06-25 | — | — | EP | disclosed |
| US-20250099600-A1 | Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-03-27 | — | — | US | disclosed |
| WO-2024239281-A1 | TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE | HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) | 2024-11-28 | — | — | WO | disclosed |
| EP-0321722-A2 | Process for obtaining dipeptides | Degussa Aktiengesellschaft (DE) | 1989-06-28 | — | — | EP | disclosed |
| EP-0234178-A1 | New 8-substituted derivatives of an anhydrooctonic acid, methods for their preparation, pharmaceutical preparations containing these and intermediates | Astra Läkemedel Aktiebolag (SE) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987003878-A1 | NEW 8-SUBSTITUTED DERIVATIVES OF AN ANHYDROOCTONIC ACID, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE AND INTERMEDIATES | Astra Läkemedel Aktiebolag (SE) | 1987-07-02 | — | — | WO | disclosed |
| EP-0209430-A2 | L-di or tripeptides possessing a biological activity for use in human and veterinary medicines, process for their obtention and medicines containing them | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) | 1987-01-21 | — | — | EP | disclosed |
| US-4554100-A | ENZYME INHIBITORS | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1985-11-19 | — | — | US | disclosed |
| US-4187216-A | ELASTASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4087520-A | Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides | BOEHRINGER MANNHEIM GMBH (DT) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008808-A1 | Method for Synthesizing Amide and/or Polypeptide Using Unprotected Amino Acid as Ammonia Component | ANPEP, PTMS, GCG | CTSK 1858/4885MME 277/4885ECE1 1773/4885 |
| US-20060178315-A1 | Irreversible cysteine protease inhibitors of legumain | LGMN, SERPINB1, SERPINA2 | CTSK 28/4885MME 36/4885ECE1 331/4885 |
| US-20250099600-A1 | Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates | KIF18B, KIF18A, KIF5B | CTSK 2951/4885MME 3629/4885ECE1 3854/4885 |
| US-20260001906-A1 | Method for Synthesizing Amide and/or Polypeptide Using Temporary Protected Amino Acid as Ammonia Component | BCAT1, BCAT2, PTMS | CTSK 2007/4885MME 950/4885ECE1 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.