SCHEMBL336045

SCHEMBL336045

Cc1cccc([PH+](c2cccc(C)c2C)c2cccc(C)c2C)c1C.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.34
ATM Q13315 1/20 0.34
TSHR P16473 2/20 0.33
ACHE P22303 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 2/20 0.31
MEN1 O00255 1/20 0.31
AKR1B10 O60218 1/20 0.31
ABCB11 O95342 1/20 0.31
DHFR P00374 1/20 0.31
LMNA P02545 1/20 0.31
MPO P05164 1/20 0.31
CYP3A4 P08684 1/20 0.31
CHRM1 P11229 1/20 0.31
CYP2C9 P11712 1/20 0.31
AKR1B1 P15121 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
AKR1C3 P42330 1/20 0.31
AKR1C2 P52895 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29582300 1.00 TRPA1 (0.34) TRPA1ATMTSHRACHESMN1; SMN2
SCHEMBL29581687 0.86 ACHE (0.38) TSHRACHELMNACYP3A4TDP1
SCHEMBL335867 0.86 ACHE (0.38) TSHRACHELMNACYP3A4TDP1
SCHEMBL8847831 0.83 ALOX12 (0.32) LMNA
SCHEMBL813875 0.78 ACHE (0.38) TRPA1TSHRACHECYP1A2LMNA
SCHEMBL8022933 0.76 TRPA1 (0.37) TRPA1ATMTSHRACHESMN1; SMN2
SCHEMBL31096441 0.74 TRPA1 (0.35) TRPA1ATMTSHRACHESMN1; SMN2
SCHEMBL1899051 0.74 TRPA1 (0.35) TRPA1ATMTSHRACHESMN1; SMN2
SCHEMBL29393435 0.74 TRPA1 (0.32) TRPA1ATMTSHRACHESMN1; SMN2
SCHEMBL29874026 0.73 TRPA1 (0.34) TRPA1ATMTSHRACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203486-B9 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-08-01 EP claimed
US-8168556-B2 Racemoselective synthesis of ansa-metallocene compounds, ansa-metallocene compounds, catalysts comprising them, process for producing an olefin polymer by use of the catalysts, and olefin homo- and copolymers LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-05-01 US claimed
EP-2203486-B1 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2012-02-29 EP claimed
US-20100261860-A1 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) 2010-10-14 US claimed
US-7074736-B2 Hydrozirconated matrix and process for polyolefin production ROHM AND HAAS COMPANY (US) 2006-07-11 US claimed
EP-0418044-B2 Metal complex compounds, process for preparation and method of use DOW CHEMICAL CO (US) 2003-08-20 EP claimed
EP-0418044-B1 Metal complex compounds, process for preparation and method of use DOW CHEMICAL CO (US) 1997-09-10 EP claimed
EP-0765882-A2 Metal complex compounds, process for preparation and method of use THE DOW CHEMICAL COMPANY (US) 1997-04-02 EP claimed
EP-4735486-A1 PROCESS Borealis GmbH (AT) 2026-05-06 EP disclosed
US-12600807-B2 Polypropylene film with improved slip performance BOREALIS AG (AT) 2026-04-14 US disclosed
EP-4722288-A1 AUTOMOTIVE COMPOSITION Borealis GmbH (AT) 2026-04-08 EP disclosed
EP-4281499-B1 FIBER REINFORCED POLYPROPYLENE COMPOSITION BOREALIS GMBH (AT) 2026-03-11 EP disclosed
US-12571144-B2 Light weight melt blown webs with improved barrier properties BOREALIS AG (AT) 2026-03-10 US disclosed
US-12539477-B2 Filtration media made from melt-blown fibers with improved filtration properties BOREALIS AG (AT) 2026-02-03 US disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
EP-0482934-A1 Use of heterocycle borate metal complexes as coordination polymerization catalysts THE DOW CHEMICAL COMPANY (US) 1992-04-29 EP disclosed
US-5066741-A Contacting monomers with complex catalyst THE DOW CHEMICAL COMPANY (US) 1991-11-19 US disclosed
US-5064802-A Cyclopentadienyl, polymerization catalysts THE DOW CHEMICAL COMPANY (US) 1991-11-12 US disclosed
EP-0421659-A2 Process for preparation of syndiotactic vinyl aromatic polymers THE DOW CHEMICAL COMPANY (US) 1991-04-10 EP disclosed
EP-0418044-A2 Metal complex compounds, process for preparation and method of use THE DOW CHEMICAL COMPANY (US) 1991-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261860-A1 RACEMOSELECTIVE SYNTHESIS OF ANSA-METALLOCENE COMPOUNDS, ANSA-METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO- AND COPOLYMERS MAOA, SNCA, ARSA TRPA1 1220/4885ATM 1503/4885TSHR 4600/4885
US-12600807-B2 Polypropylene film with improved slip performance CCRL2, CCR1, CCR6 TRPA1 3627/4885ATM 3917/4885TSHR 2760/4885
US-12571144-B2 Light weight melt blown webs with improved barrier properties HMGB2, HMOX2, HPGDS TRPA1 663/4885ATM 3852/4885TSHR 1716/4885
US-12539477-B2 Filtration media made from melt-blown fibers with improved filtration properties MACF1, MIF, TGFBR2 TRPA1 59/4885ATM 1441/4885TSHR 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.