Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL336488

CCOC(=O)C(CC)CC.N

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 1/20 0.44
ALOX15 P16050 1/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
SOAT1 P35610 1/20 0.43
CPB2 Q96IY4 2/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TRPA1 O75762 1/20 0.40
RAB9A P51151 1/20 0.39
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.39
EPHX2 P34913 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284647 0.97 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10MEN1NPC1
SCHEMBL4957929 0.94 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10MEN1NPC1
Hydrochloric Acid SCHEMBL27554398 0.94 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10MEN1NPC1
SCHEMBL21981164 0.94 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10MEN1NPC1
SCHEMBL28145904 0.94 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10MEN1NPC1
SCHEMBL29207090 0.94 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10MEN1NPC1
SCHEMBL28904001 0.94 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10MEN1NPC1
SCHEMBL27524668 0.90 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10MEN1NPC1
Hexane SCHEMBL5202053 0.87 CA2 (0.52) ALDH1A1LMNAHSD17B10MEN1NPC1
Phosphonic Acid SCHEMBL7247578 0.87 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117758374-A On-DNA alpha-hydroxy olefin lead compound and synthesis method thereof 康龙化成(宁波)科技发展有限公司 2024-03-26 CN claimed
CN-114853822-A Oligonucleotide-disulfide and synthetic method thereof 康龙化成(宁波)科技发展有限公司 2022-08-05 CN claimed
EP-1438437-B1 METHOD FOR THE DETECTION OF CYTOSINE METHYLATION IN IMMOBILISED DNA SAMPLES EPIGENOMICS AG (DE) 2009-04-22 EP claimed
US-4005129-A OXALATE ESTERS ATLANTIC RICHFIELD COMPANY (US) 1977-01-25 US claimed
US-12637672-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2026-05-26 US disclosed
EP-3801553-B1 PRODRUGS OF FULVESTRANT KASHIV BIOSCIENCES LLC (US) 2026-03-25 EP disclosed
US-20260076989-A1 OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD (SG) 2026-03-19 US disclosed
US-20260009012-A1 ENGINEERED PHOSPHOPENTOMUTASE VARIANT ENZYMES CODEXIS, INC. (US) 2026-01-08 US disclosed
US-20250320494-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION E-THERAPEUTICS PLC (GB) 2025-10-16 US disclosed
US-20250313836-A1 CHIRAL DESIGN WAVE LIFE SCIENCES LTD (SG) 2025-10-09 US disclosed
US-12421509-B2 Engineered phosphopentomutase variant enzymes CODEXIS, INC. (US) 2025-09-23 US disclosed
US-20250281622-A1 FN3 DOMAIN-siRNA CONJUGATES AND USES THEREOF Aro Biotherapeutics Company 2025-09-11 US disclosed
EP-0212951-A2 Labelled nucleic acids AMOCO CORPORATION (US) 1987-03-04 EP disclosed
EP-0210021-A2 Carbonic anhydrase inhibitor-tagged nucleic acid probes SISKA DIAGNOSTICS,INC. (US) 1987-01-28 EP disclosed
EP-0209996-A2 Nucleic acid probes comprising N4 -(substituted amino)cytidines SISKA DIAGNOSTICS,INC. (US) 1987-01-28 EP disclosed
CN-85104701-A Produce the method for useful matter 1986-12-17 CN disclosed
US-4552764-A Peptides for control of intestinal motility RESEARCH CORPORATION (US) 1985-11-12 US disclosed
EP-0097373-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1984-01-04 EP disclosed
US-4281142-A Imidazolecarboxaldehydes HOFFMANN-LA ROCHE INC. (US) 1981-07-28 US disclosed
US-4194049-A 2-[[2-Methyl-1-[2-benzoyl(or benzyl)phenyl]-1H-imidazol-5-yl]methyl]-1H-isoindole-1,3(2H)-diones HOFFMANN-LA ROCHE INC. (US) 1980-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009012-A1 ENGINEERED PHOSPHOPENTOMUTASE VARIANT ENZYMES PPME1, PPA1, ITPA ALDH1A1 3787/4885LMNA 4597/4885HSD17B10 2615/4885
US-20260076989-A1 OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF NSUN2, TLR9, MSR1 ALDH1A1 4430/4885LMNA 1684/4885HSD17B10 3942/4885
US-12637672-B2 Oligonucleotide compositions and methods thereof UPF1, SMN1; SMN2, RNGTT ALDH1A1 3106/4885LMNA 870/4885HSD17B10 4756/4885
US-20250320494-A1 INHIBITORS OF EXPRESSION AND/OR FUNCTION SERPINC1, TFPI2, SERPINB1 ALDH1A1 1796/4885LMNA 2527/4885HSD17B10 1395/4885
US-20250281622-A1 FN3 DOMAIN-siRNA CONJUGATES AND USES THEREOF FN1, ITGB3, FNIP1 ALDH1A1 4563/4885LMNA 1379/4885HSD17B10 4459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.