Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Pyruvate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL598199 | 0.96 | — | — | |
| Pyruvate SCHEMBL7941746 | 0.92 | CA4 (0.83) | — | |
| Pyruvate SCHEMBL7935573 | 0.92 | CA4 (0.83) | — | |
| Pyruvate SCHEMBL1953085 | 0.92 | CA4 (0.83) | — | |
| Pyruvate SCHEMBL7031058 | 0.92 | CA4 (0.83) | — | |
| Pyruvate SCHEMBL27565126 | 0.92 | — | — | |
| Pyruvate SCHEMBL148220 | 0.91 | — | — | |
| Pyruvate SCHEMBL1332703 | 0.87 | — | — | |
| Pyruvate SCHEMBL6743471 | 0.87 | CA4 (0.91) | — | |
| Pyruvate SCHEMBL18226 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8574896-B2 | Colorimetric method and reagent used for the same | ARKRAY, INC. (JP) | 2013-11-05 | — | — | US | disclosed |
| EP-1942195-B1 | Colorimetric method and reagent used for the same | ARKRAY INC (JP) | 2010-09-22 | — | — | EP | disclosed |
| US-20090233322-A1 | COLORIMETRIC METHOD AND REAGENT USED FOR THE SAME | ARKRAY, INC. (JP) | 2009-09-17 | — | — | US | disclosed |
| US-7550273-B2 | Colorimetric method and reagent used for the same | ARKRAY, INC. (JP) | 2009-06-23 | — | — | US | disclosed |
| EP-1457572-B1 | METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN | ARKRAY INC (JP) | 2009-03-25 | — | — | EP | disclosed |
| EP-1466987-B1 | METHOD OF COLORIMETRY | ARKRAY INC (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1942195-A1 | Colorimetric method and reagent used for the same | Arkray, Inc. (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20050014213-A1 | Method of colorimetry and reagent for use therein | ARKRAY, INC. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1466987-A1 | METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN | ARKRAY, Inc. (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-1457572-A1 | METHOD OF COLORIMETRY AND REAGENT FOR USE THEREIN | ARKRAY, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |