Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.79 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | FABP3 | P05413 | 6/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377800 | 1.00 | CA2 (0.79) | CA2NFKB1GPR84CA1CYP3A4 | |
| SCHEMBL15268876 | 1.00 | CA2 (0.79) | CA2NFKB1GPR84CA1CYP3A4 | |
| Lithium Ion SCHEMBL9781566 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| Potassium Ion SCHEMBL9246555 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| SCHEMBL3438387 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| Lithium Ion SCHEMBL5680426 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| SCHEMBL16972964 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| SCHEMBL9577313 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| Lithium Ion SCHEMBL11438840 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 | |
| SCHEMBL3685429 | 0.96 | CA2 (0.72) | CA2NFKB1GPR84CA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1629078-B1 | IMPROVED CLEANING COMPOSITION | UNILEVER PLC (GB) | 2010-10-06 | — | — | EP | disclosed |
| US-20060122081-A1 | Cleaning composition | HINDUSTAN LEVER LIMITED (IN) | 2006-06-08 | — | — | US | disclosed |
| EP-1629078-A1 | IMPROVED CLEANING COMPOSITION | Unilever Plc (GB) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108877-A1 | IMPROVED CLEANING COMPOSITION | UNILEVER PLC (GB) | 2004-12-16 | — | — | WO | disclosed |