Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3369280

CCCCC=Cc1cccc2c1-c1ccccc1C2.[Cl-].[Cl-].[Zr+2]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.30
CHRM1 known ✓ P11229 1/20 0.30
CHRM3 known ✓ P20309 1/20 0.30
CYSLTR2 Q9NS75 2/20 0.36
CYSLTR1 Q9Y271 2/20 0.36
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
SIGMAR1 Q99720 2/20 0.33
PDE5A O76074 1/20 0.33
ALOX12 P18054 1/20 0.32
POLB P06746 1/20 0.32
HTR2B P41595 1/20 0.32
MAOA P21397 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
OXER1 Q8TDS5 1/20 0.31
POLM Q9NP87 1/20 0.31
POLK Q9UBT6 1/20 0.31
POLL Q9UGP5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27762485 0.80 PNMT (0.43) CYSLTR2CYSLTR1DRD2DRD4DRD3
Hydrochloric Acid SCHEMBL3369277 0.73 TSHR (0.37) DRD2DRD4DRD3SIGMAR1ALOX12
SCHEMBL1469736 0.71 PDE5A (0.41) CYSLTR2CYSLTR1PDE5A
SCHEMBL1469737 0.71 PDE5A (0.41) CYSLTR2CYSLTR1PDE5A
SCHEMBL8715941 0.71 PNMT (0.45) CYSLTR2CYSLTR1DRD2DRD4DRD3
SCHEMBL9162757 0.70 DRD2 (0.44) DRD2DRD4DRD3SIGMAR1POLB
SCHEMBL6046925 0.69 CYSLTR2 (0.50) CYSLTR2CYSLTR1PDE5ATLR8
Fluorene SCHEMBL25291666 0.69 MAOA (0.50) DRD2SIGMAR1ALOX12HTR2BMAOA
SCHEMBL2416249 0.69 LIPG (0.44) CYSLTR2CYSLTR1DRD2DRD4DRD3
SCHEMBL2120191 0.69 MAOA (0.47) POLBHTR2BMAOANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6232415-B1 Process to produce a monovinylaromatic/ monoolefin polymer and said monovinylaromatic/monoolefin polymer PHILLIPS PETROLEUM COMPANY 2001-05-15 US claimed
EP-0853549-B1 FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE CHEVRON PHILLIPS CHEMICAL CO (US) 2010-10-13 EP disclosed
US-6355359-B1 CLARITY PHILLIPS PETROLEUM COMPANY 2002-03-12 US disclosed
US-6214469-B1 Films comprising metallocene catalyzed polyethylene PHILLIPS PETROLEUM COMPANY 2001-04-10 US disclosed
EP-0853549-A4 FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE PHILLIPS PETROLEUM CO (US) 1999-08-18 EP disclosed
EP-0853549-A1 FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE Phillips Petroleum Company (US) 1998-07-22 EP disclosed
WO-1997006951-A1 FILMS COMPRISING METALLOCENE CATALYZED POLYETHYLENE PHILLIPS PETROLEUM COMPANY (US) 1997-02-27 WO disclosed