SCHEMBL336967

SCHEMBL336967

Cc1[c]c(-c2ccccc2C)ccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
ACHE P22303 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CYP3A4 P08684 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2A6 P11509 2/20 0.33
HTR7 P34969 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MYC P01106 1/20 0.33
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
IDO1 P14902 1/20 0.33
METAP2 P50579 1/20 0.33
FLT1 P17948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5153405 0.89 TSHR (0.43) TSHRNPC1RAB9ASMN1; SMN2ACHE
SCHEMBL8125766 0.87 TRPA1 (0.38) TSHRSMN1; SMN2ACHECYP2A6ALDH1A1
SCHEMBL712397 0.80 ACHE (0.39) TSHRNPC1RAB9ASMN1; SMN2ACHE
SCHEMBL28461076 0.79 ALDH1A1 (0.39) TSHRNPC1RAB9ASMN1; SMN2ACHE
SCHEMBL7951323 0.78 ACHE (0.33) TSHRACHECYP3A4CYP2A6ALDH1A1
SCHEMBL29104471 0.78 CYP1A2 (0.50) TSHRSMN1; SMN2CYP3A4TDP1CYP2A6
SCHEMBL29104477 0.78 ALDH1A1 (0.43) TSHRTDP1CYP2A6ALDH1A1CYP1A2
SCHEMBL818637 0.75 NPC1 (0.35) TSHRNPC1RAB9ASMN1; SMN2ACHE
SCHEMBL1803708 0.73 ALDH1A1 (0.36) TSHRNPC1RAB9ASMN1; SMN2ACHE
SCHEMBL981109 0.71 TSHR (0.39) TSHRNPC1RAB9ASMN1; SMN2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-04-04 US claimed
EP-4270508-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP claimed
US-20230232700-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-07-20 US claimed
US-20230165124-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-05-25 US claimed
US-11581487-B2 Patterned conductive coating for surface of an opto-electronic device OTI LUMIONICS INC. (CA) 2023-02-14 US claimed
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-04-04 US disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
EP-4270508-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-01 EP disclosed
US-11785831-B2 Method for patterning a coating on a surface and device including a patterned coating OTI LUMIONICS INC. (CA) 2023-10-10 US disclosed
US-20230232700-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-07-20 US disclosed
US-11706969-B2 Method for patterning a coating on a surface and device including a patterned coating OTI LUMIONICS INC. (CA) 2023-07-18 US disclosed
US-20230165124-A1 METHOD FOR PATTERNING A COATING ON A SURFACE AND DEVICE INCLUDING A PATTERNED COATING OTI LUMIONICS INC. (CA) 2023-05-25 US disclosed
US-4401455-A REACTING AN N-DIARYLPHOSPHONOMETHYL GLYCINE ESTER WITH AN ALKYL SULFENYL CHLORIDE; POSTEMERGENCE HERBICIDES MONSANTO COMPANY (US) 1983-08-30 US disclosed
US-4401604-A Process for preparing thiosulfenamide derivatives of N-phosphonomethylglycine triesters MONSANTO COMPANY (US) 1983-08-30 US disclosed
US-4395374-A HERBICIDES, PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1983-07-26 US disclosed
US-4395276-A Thiosulfenamide derivatives of N-phosphonomethylglycinonitriles as herbicides MONSANTO COMPANY (US) 1983-07-26 US disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed
EP-0055925-A2 Alkyl N-arylsulfenyl-N-diaryloxy-phosphinylmethylglycinates and their use as herbicides MONSANTO COMPANY (US) 1982-07-14 EP disclosed
US-4300943-A Ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-11-17 US disclosed
US-4252554-A Herbicidal ester derivatives of N-arylthio-N-phosphonomethylglycinonitrile MONSANTO COMPANY (US) 1981-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240114784-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYBA TSHR 4436/4885NPC1 3130/4885RAB9A 3061/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.