Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523837 | 0.78 | MAOA (0.39) | MAOACA12CA1CA2CA9 | |
| SCHEMBL3395053 | 0.74 | ALDH1A1 (0.48) | CA12CA1CA2CA9LMNA | |
| SCHEMBL27649553 | 0.74 | LMNA (0.44) | MAOACA12CA1CA2CA9 | |
| SCHEMBL3389375 | 0.71 | CA2 (0.40) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9038242 | 0.65 | MYC (0.52) | GAAKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL3394006 | 0.64 | AGBL2 (0.33) | GAAKDM4EMEN1KMT2AMAPT | |
| SCHEMBL28627643 | 0.63 | EGFR (0.57) | CA12CA1CA2CA9GAA | |
| SCHEMBL10814976 | 0.63 | NR1H4 (0.62) | GAAKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL3981200 | 0.63 | KMT2A (0.45) | CA12CA1CA2CA9GAA | |
| SCHEMBL3981152 | 0.63 | PTGDR2 (0.47) | CA12CA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | MAOA 1802/4885CA12 4101/4885CA1 4367/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | MAOA 2475/4885CA12 4557/4885CA1 4607/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | MAOA 2273/4885CA12 4493/4885CA1 4765/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | MAOA 1802/4885CA12 4101/4885CA1 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.