Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.39 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.39 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.38 |
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.38 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.38 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386214 | 1.00 | L3MBTL1 (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| SCHEMBL28724094 | 0.96 | L3MBTL1 (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| Lithium Ion SCHEMBL11426853 | 0.96 | L3MBTL1 (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| Potassium Ion SCHEMBL29386357 | 0.96 | L3MBTL1 (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| Potassium Ion SCHEMBL6028409 | 0.96 | L3MBTL1 (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| Tetramethylammonium Ion SCHEMBL29690735 | 0.90 | L3MBTL1 (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| SCHEMBL7098523 | 0.84 | L3MBTL1 (0.45) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| SCHEMBL29575161 | 0.83 | TSHR (0.44) | L3MBTL1TSHRTDP1ALDH1A1CYP3A4 | |
| SCHEMBL713915 | 0.83 | LMNA (0.47) | TDP1ALDH1A1CYP3A4HTR6PKM | |
| SCHEMBL30461613 | 0.83 | LMNA (0.47) | TDP1ALDH1A1CYP3A4HTR6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114752035-B | High-solid-content aqueous polyurethane dispersion and preparation method and application thereof | 浙江大学衢州研究院 | 2024-07-05 | — | — | CN | claimed |
| CN-118085801-A | Aluminum-silver conductive silica gel for electromagnetic shielding and production process thereof | 东莞鸿兴橡塑科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116178984-B | Bright yellow reactive dye and preparation method thereof | 湖北丽源科技股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117924660-A | Preparation method and application of emulsifier applied to acidic resin emulsification | 襄阳精信汇明科技股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117887283-A | Preparation method of water-soluble yellow reactive dye | 浙江劲光实业股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117777754-A | Orange reactive dye with high fastness and preparation method thereof | 湖北丽源科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117619169-A | Anion exchange membrane for separating nitrogen and phosphorus ions in water and preparation method thereof | 浙江工业大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117567874-A | Bright yellow reactive dye and preparation method thereof | 湖北华丽染料工业有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117510385-A | Chain transfer agent for polycarboxylate superplasticizer, application and preparation method thereof | 科之杰新材料集团(贵州)有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-117511487-A | Preparation method of PDI (polyurethane) aqueous polyurethane adhesive | 甘肃银光聚银化工有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-113563560-A | Waterborne polyurethane wet rubbing color fastness improver | 江门市弘创新材料有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113122122-A | High-solid-content polyurethane ink resin, preparation method and application thereof | 万华化学（北京）有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-212701893-U | Efficient tail gas processing apparatus of 2, 4-diaminobenzene sodium sulfonate production usefulness | 绍兴上虞联谊化工有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-112300438-A | Gas-barrier moisture-permeable film and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-109679369-B | Preparation method of yellow reactive dye | 浙江劲光实业股份有限公司 | 2020-08-04 | — | — | CN | claimed |
| CN-107814928-B | Modified polyisophthaloyl metaphenylene diamine easy to dye by cationic dye and preparation method and application thereof | 东华大学 | 2020-04-21 | — | — | CN | claimed |
| CN-106380569-B | A kind of aqueous polyurethane Anti Glare Coatings material and preparation method thereof | 华南理工大学 | 2019-01-15 | — | — | CN | claimed |
| CN-107417873-A | A kind of aqueous polyurethane dispersion and its non-solvent preparation | 中国科学院长春应用化学研究所 | 2017-12-01 | — | — | CN | claimed |
| CN-106380569-A | Water-based polyurethane anti-glare coating material and preparation method thereof | 华南理工大学 | 2017-02-08 | — | — | CN | claimed |
| EP-2248860-A1 | AN ORANGE ACTIVE DYE AND THE PREPARATION THEREOF | Tianjin Dek Chemical Co., Ltd (CN) | 2010-11-10 | — | — | EP | claimed |