SCHEMBL340999

SCHEMBL340999

CN(Cc1ccccc1)CC(C)(C)C=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.46
PRMT6 Q96LA8 1/20 0.46
PRMT8 Q9NR22 1/20 0.46
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
LMNA P02545 2/20 0.44
USP2 O75604 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
PYCR1 P32322 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
BLM P54132 1/20 0.43
RIPK1 Q13546 1/20 0.42
AOC3 Q16853 1/20 0.42
SIGMAR1 Q99720 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TMEM97 Q5BJF2 1/20 0.42
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28814049 0.83 SIGMAR1 (0.49) ALDH1A1AOC3SIGMAR1TMEM97
SCHEMBL9281673 0.79 ALDH1A1 (0.54) CARM1PRMT6PRMT8ALDH1A1TSHR
SCHEMBL340966 0.78 MEN1 (0.41) ALDH1A1TSHRRIPK1SIGMAR1MEN1
SCHEMBL342937 0.77 LMNA (0.46) ALDH1A1TSHRLMNARIPK1MEN1
SCHEMBL24926944 0.76 ALDH1A1 (0.50) CARM1PRMT6PRMT8ALDH1A1TSHR
SCHEMBL7264487 0.76 ALDH1A1 (0.50) CARM1PRMT6PRMT8ALDH1A1TSHR
SCHEMBL19715624 0.76 ALDH1A1 (0.50) CARM1PRMT6PRMT8ALDH1A1TSHR
SCHEMBL4482337 0.76 CARM1 (0.55) CARM1PRMT6PRMT8ALDH1A1TSHR
SCHEMBL2198151 0.74 TSHR (0.48) CARM1PRMT6PRMT8ALDH1A1TSHR
SCHEMBL1601728 0.74 MEN1 (0.41) ALDH1A1TSHRMAOBRIPK1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP claimed
CN-103261146-B Polyamines having secondary aliphatic amino groups SIKA TECHNOLOGY AG (CH) 2016-01-27 CN claimed
US-8877955-B2 Secondary aminosilanes SIKA TECHNOLOGY AG (CH) 2014-11-04 US claimed
US-20130281562-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2013-10-24 US claimed
EP-2651876-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP claimed
US-20130261270-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-10-03 US claimed
CN-103313995-A Secondary aminosilanes SIKA TECHNOLOGY AG 2013-09-18 CN claimed
CN-103261146-A Polyamines having secondary aliphatic amino groups SIKA TECHNOLOGY AG 2013-08-21 CN claimed
EP-2468759-A1 Secondary Aminosilanes Sika Technology AG (CH) 2012-06-27 EP claimed
WO-2012080265-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
EP-2465843-A1 Polyamines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP claimed
EP-3484898-B1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE MOMENTIVE PERFORMANCE MAT INC (US) 2023-06-28 EP disclosed
EP-4053134-A1 METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE Momentive Performance Materials Inc. (US) 2022-09-07 EP disclosed
US-11230563-B2 Method of stabilizing imino-functional silane MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-01-25 US disclosed
US-11149106-B2 Two-component polyurethane adhesive having substantially temperature-independent mechanical properties and high strength SIKA TECHNOLOGY AG (CH) 2021-10-19 US disclosed
US-20100101455-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-04-29 US disclosed
EP-2178828-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE Sika Technology AG (CH) 2010-04-28 EP disclosed
CN-101687775-A Aldimines and compositions comprising aldamine SIKA TECHNOLOGY AG 2010-03-31 CN disclosed
WO-2009010522-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE SIKA TECHNOLOGY AG (CH) 2009-01-22 WO disclosed
EP-2017260-A1 Aldimines and compounds containing aldimine Sika Technology AG (CH) 2009-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11230563-B2 Method of stabilizing imino-functional silane INF2, RNF168, BOLA2; BOLA2B CARM1 1051/4885PRMT6 1566/4885PRMT8 243/4885
US-20130281562-A1 SECONDARY AMINOSILANES AS3MT, SRM, MSN CARM1 396/4885PRMT6 30/4885PRMT8 84/4885
US-20100101455-A1 ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE ALDH7A1, ILK, ALDH3A1 CARM1 285/4885PRMT6 486/4885PRMT8 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.