SCHEMBL342161

SCHEMBL342161

CCOC(=O)C1=NOC(Cc2ccc(Cl)cc2Cl)C1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
ALDH1A1 P00352 4/20 0.47
CYP3A4 P08684 2/20 0.45
POLB P06746 2/20 0.45
CYP2C19 P33261 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
HTT P42858 1/20 0.44
CYP2C9 P11712 1/20 0.43
MAPT P10636 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPK1 P28482 1/20 0.42
PDE3B Q13370 1/20 0.41
PDE3A Q14432 1/20 0.41
LMNA P02545 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312028 0.88 F10 (0.41) L3MBTL1SMN1; SMN2LMNAKMT2A
SCHEMBL1830918 0.83 LMNA (0.49) SMN1; SMN2NPC1TSHRLMNAKMT2A
SCHEMBL4142817 0.82 FAAH (0.52) L3MBTL1ALDH1A1SMN1; SMN2HTTMAPT
SCHEMBL168434 0.82 CYP3A4 (0.42) L3MBTL1ALDH1A1CYP3A4SMN1; SMN2CYP2C9
SCHEMBL6641706 0.78 KDM4E (0.40) CYP3A4CYP2C19SMN1; SMN2HTTCYP2C9
SCHEMBL892286 0.76 ALDH1A1 (0.58) L3MBTL1ALDH1A1CYP3A4POLBCYP2C19
SCHEMBL6645241 0.75 SLC6A2 (0.38) L3MBTL1CYP2C19MEN1KMT2A
SCHEMBL1009619 0.74 ALDH1A1 (0.54) L3MBTL1ALDH1A1CYP3A4POLBCYP2C19
SCHEMBL20020312 0.74 ALDH1A1 (0.51) L3MBTL1ALDH1A1CYP3A4POLBCYP2C19
SCHEMBL892545 0.73 ALDH1A1 (0.54) L3MBTL1ALDH1A1CYP3A4POLBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1083 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113367128-B Composition containing R-oxadiazolyl aryl formamide compound and safener and application thereof 江苏清原农冠杂草防治有限公司 2023-04-28 CN claimed
CN-113367128-A Composition containing R-type oxadiazolyl aryl formamide compound and safener and application thereof 江苏清原农冠杂草防治有限公司 2021-09-10 CN claimed
EP-2099751-B1 BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS BAYER IP GMBH (DE) 2018-05-30 EP claimed
US-20160000076-A1 Fungicidal Active Compound Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-07 US claimed
EP-2185563-B1 OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES BAYER IP GMBH (DE) 2015-08-19 EP claimed
EP-1943218-B1 ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS BAYER IP GMBH (DE) 2015-05-06 EP claimed
US-8993782-B2 Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives BAYER CROPSCIENCE AG (DE) 2015-03-31 US claimed
EP-2195290-B1 HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES BAYER IP GMBH (DE) 2015-03-11 EP claimed
EP-1771067-B1 SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS BAYER CROPSCIENCE AG (DE) 2014-03-12 EP claimed
US-8629084-B2 Iodine-phenyl-substituted cyclic cetoenols BAYER CROPSCIENCE AG (DE) 2014-01-14 US claimed
US-20060160847-A1 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives BAYER CROPSCIENCE AG (DE) 2006-07-20 US claimed
EP-1303189-B1 ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES BAYER CROPSCIENCE AG (DE) 2005-08-24 EP claimed
EP-1515606-A2 COMBINATIONS OF HERBICIDAL AROMATIC CARBOXYLIC ACIDS AND SAFENERS Bayer CropScience GmbH (DE) 2005-03-23 EP claimed
US-20050054535-A1 Selective herbicides based on substituted cyclic keto-enols and safeners BAYER CROPSCIENCE AG (DE) 2005-03-10 US claimed
US-20050009705-A1 Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-13 US claimed
US-20040132619-A1 Selective substituted aryl ketone and safener based herbicides BAYER CROPSCIENCE K.K. (JP) 2004-07-08 US claimed
WO-2003103394-A2 COMBINATIONS OF HERBICIDAL AROMATIC CARBOXYLIC ACIDS AND SAFENERS BAYER CROPSCIENCE GMBH (DE) 2003-12-18 WO claimed
US-20030232725-A1 Combinations of herbicidal aromatic carboxylic acids and safeners BAYER CROPSCIENCE AG (DE) 2003-12-18 US claimed
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-13 US claimed
US-5441922-A Blended with quinoline and phenylazole derivatives as safening agents HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides AADAC, CBR3, ABAT L3MBTL1 1445/4885ALDH1A1 591/4885CYP3A4 810/4885
US-20040132619-A1 Selective substituted aryl ketone and safener based herbicides CYP2W1, CYP4Z1, CYP2E1 L3MBTL1 941/4885ALDH1A1 66/4885CYP3A4 54/4885
US-20050009705-A1 Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners TARS2, TST, DDT L3MBTL1 176/4885ALDH1A1 547/4885CYP3A4 173/4885
US-20050054535-A1 Selective herbicides based on substituted cyclic keto-enols and safeners DDT, LAGE3, KYAT1 L3MBTL1 460/4885ALDH1A1 2061/4885CYP3A4 144/4885
US-20030232725-A1 Combinations of herbicidal aromatic carboxylic acids and safeners DDT, CYP2W1, AADAC L3MBTL1 559/4885ALDH1A1 800/4885CYP3A4 203/4885
US-20160000076-A1 Fungicidal Active Compound Combinations DDT, CYP4X1, CYP51A1 L3MBTL1 1603/4885ALDH1A1 516/4885CYP3A4 28/4885
US-20060160847-A1 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives DDT, DDC, DAO L3MBTL1 828/4885ALDH1A1 2610/4885CYP3A4 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.