Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422770 | 1.00 | LMNA (0.54) | LMNAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL12308190 | 0.87 | KMT2A (0.53) | KDM4EALDH1A1GAAELANEKMT2A | |
| SCHEMBL30059085 | 0.85 | KDM4E (0.46) | KDM4EHPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL17614815 | 0.85 | KDM4E (0.56) | LMNAKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL30600058 | 0.84 | ALDH1A1 (0.51) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL2327455 | 0.84 | CTSD (0.56) | LMNAHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL2327457 | 0.84 | CTSD (0.56) | LMNAHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL17080362 | 0.84 | ALDH1A1 (0.49) | LMNAKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL29104354 | 0.84 | ALDH1A1 (0.51) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL12308265 | 0.84 | FNTA (0.47) | KDM4EHPGDALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708245-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708245-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708245-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160083336-A1 | FATTY ACID ACYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2016-03-24 | — | — | US | disclosed |
| US-20160083336-A1 | FATTY ACID ACYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2016-03-24 | — | — | US | disclosed |
| US-20160083336-A1 | FATTY ACID ACYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2016-03-24 | — | — | US | disclosed |
| US-9085527-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085527-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-9085527-B2 | Fatty acid acylated salicylates and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |
| US-8946451-B2 | Lipoic acid acylated salicylate derivatives and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| US-8846972-B2 | — | — | 2014-09-30 | — | — | US | disclosed |
| WO-2011044140-A1 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011044138-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20110082120-A1 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082120-A1 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
| US-20100184730-A1 | Fatty Acid Acylated Salicylates and Their Uses | CATABASIS PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-20100184730-A1 | Fatty Acid Acylated Salicylates and Their Uses | CATABASIS PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
| US-20100184730-A1 | Fatty Acid Acylated Salicylates and Their Uses | CATABASIS PHARMACEUTICALS, INC. | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082120-A1 | SUBSTITUTED THIOACETIC ACID SALICYLATE DERIVATIVES AND THEIR USES | TST, SLC5A2, ACACA | LMNA 4672/4885KDM4E 4030/4885HPGD 1097/4885 |
| US-20110082192-A1 | LIPOIC ACID ACYLATED SALICYLATE DERIVATIVES AND THEIR USES | ACACA, ACAT2, ACACB | LMNA 2301/4885KDM4E 2682/4885HPGD 407/4885 |
| US-20160083336-A1 | FATTY ACID ACYLATED SALICYLATES AND THEIR USES | FADS1, FASN, ALOX5 | LMNA 3266/4885KDM4E 3068/4885HPGD 338/4885 |
| US-20100184730-A1 | Fatty Acid Acylated Salicylates and Their Uses | FADS1, FASN, ALOX5 | LMNA 3266/4885KDM4E 3068/4885HPGD 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.