SCHEMBL3423927

SCHEMBL3423927

Cc1ccc(-c2ccc(C)cc2-n2c3ccccc3c3ccccc32)c(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 1/20 0.41
NTRK1 P04629 1/20 0.41
ALDH1A1 P00352 2/20 0.41
GPR3 P46089 1/20 0.40
BCHE P06276 2/20 0.39
ACHE P22303 2/20 0.39
ELANE P08246 1/20 0.38
POLB P06746 1/20 0.38
TDO2 P48775 1/20 0.38
IDO2 Q6ZQW0 1/20 0.38
MPI P34949 2/20 0.37
PHOSPHO1 Q8TCT1 2/20 0.37
PMM2 O15305 1/20 0.37
KIF11 P52732 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29089281 0.92 LMNA (0.39) LMNAMAPTHTTKDM4EATM
SCHEMBL20110483 0.88 MAPT (0.41) LMNAMAPTHTTKDM4EATM
SCHEMBL13235741 0.85 TDO2 (0.48) LMNAMAPTHTTKDM4EATM
SCHEMBL17059040 0.85 MPI (0.47) LMNAMAPTHTTKDM4EATM
SCHEMBL26226118 0.84 BCHE (0.43) LMNAMAPTHTTKDM4EATM
SCHEMBL26481413 0.84 ALDH1A1 (0.41) LMNAMAPTHTTKDM4EATM
SCHEMBL26340818 0.84 ALDH1A1 (0.41) LMNAMAPTHTTKDM4EATM
SCHEMBL25919679 0.84 BCHE (0.43) LMNAMAPTHTTKDM4EATM
SCHEMBL24268709 0.83 TDO2 (0.45) LMNAMAPTHTTKDM4EATM
SCHEMBL13071615 0.83 LMNA (0.33) LMNAMAPTHTTKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10454042-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-10-22 US disclosed
US-9287515-B2 Compositions comprising organic and organometallic compounds, and their applications in organic electroluminescence, light emission, display, and illumination devices UDC Ireland (IE) 2016-03-15 US disclosed
EP-2765174-A1 Organic electroluminescent element, and display and illuminator Konica Minolta Holdings, Inc. (JP) 2014-08-13 EP disclosed
EP-2762546-A1 Organic electroluminescent element, and display and illuminator Konica Minolta Holdings, Inc. (JP) 2014-08-06 EP disclosed
EP-2759585-A1 Organic electroluminescent element, and display and illuminator Konica Minolta Business Technologies, Inc. (JP) 2014-07-30 EP disclosed
EP-1956022-B1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL CO (JP) 2012-07-25 EP disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153272-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120091445-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-04-19 US disclosed
US-20120091445-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-04-19 US disclosed
US-7993760-B2 Compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-09 US disclosed
US-7993760-B2 Compound for use in organic electroluminescent device and organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2011-08-09 US disclosed
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2009-12-10 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
US-7629060-B2 Liquid crystal cells; durability, stability; brightness ; containing carbazole compound KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-08 US disclosed
EP-1956022-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2008-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090302742-A1 Compound for Use in Organic Electroluminescent Device and Organic Electroluminescent Device LAGE3, ICMT, PPOX LMNA 1470/4885MAPT 445/4885HTT 4204/4885
US-20120091445-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, OR10J3 LMNA 4773/4885MAPT 1144/4885HTT 4577/4885
US-10454042-B2 Organic electroluminescence device EML4, ELOC, ORC3 LMNA 1742/4885MAPT 503/4885HTT 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.