SCHEMBL343246

SCHEMBL343246

CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)O[C@](OC(=O)[C@]2(O)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)COC(C)=O)O2)(C(=O)O)C[C@@H]1O

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.46
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
MAG P20916 3/20 0.41
SIGLEC7 Q9Y286 7/20 0.41
CD22 P20273 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3493295 0.95 NANP (0.47) NANPL3MBTL1SELLSELPMAG
SCHEMBL358286 0.94 NANP (0.56) NANPL3MBTL1SELLSELPMAG
SCHEMBL284328 0.89 NANP (0.52) NANPL3MBTL1SELLSELPMAG
SCHEMBL593858 0.89 NANP (0.52) NANPL3MBTL1SELLSELPMAG
SCHEMBL1073940 0.89 NANP (0.52) NANPL3MBTL1SELLSELPMAG
SCHEMBL9479903 0.88 NANP (0.51) NANPL3MBTL1SELLSELPMAG
SCHEMBL9697921 0.86 NANP (0.59) NANPL3MBTL1SELLSELPMAG
SCHEMBL13190787 0.85 NANP (0.67) NANPL3MBTL1SELLSELPMAG
SCHEMBL442944 0.85 NANP (0.61) NANPL3MBTL1SELLSELPMAG
SCHEMBL420656 0.85 NANP (0.67) NANPL3MBTL1SELLSELPMAG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029780-B2 Long-acting polypeptides and methods of producing and administering same OPKO BIOLOGICS LTD. (IL) 2024-07-09 US disclosed
US-20220241380-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME OPKO BIOLOGICS LTD. (IL) 2022-08-04 US disclosed
US-11197915-B2 Long-acting polypeptides and methods of producing and administering same OPKO BIOLOGICS LTD. (IL) 2021-12-14 US disclosed
EP-3763733-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME OPKO Biologics Ltd. (IL) 2021-01-13 EP disclosed
EP-3060239-B1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME OPKO BIOLOGICS LTD (IL) 2020-05-13 EP disclosed
US-20200131242-A1 METHODS OF TREATMENT WITH LONG-ACTING HORMONE OPKO BIOLOGICS LTD. (IL) 2020-04-30 US disclosed
US-10351615-B2 Methods of treatment with long-acting growth hormone OPKO BIOLOGICS LTD. (IL) 2019-07-16 US disclosed
EP-3482765-A1 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME OPKO Biologics Ltd. (IL) 2019-05-15 EP disclosed
US-10221228-B2 Long-acting polypeptides and methods of producing and administering same OPKO BIOLOGICS LTD. (IL) 2019-03-05 US disclosed
EP-2739298-B1 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME OPKO BIOLOGICS LTD (IL) 2018-10-03 EP disclosed
US-20130184207-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME PROLOR BIOTECH INC. (IL) 2013-07-18 US disclosed
US-8450269-B2 Long-acting growth hormone and methods of producing same Prolor Biotech Ltd. (IL) 2013-05-28 US disclosed
US-8426166-B2 Long-acting polypeptides and methods of producing same PROLOR BIOTECH INC. (IL) 2013-04-23 US disclosed
WO-2013018098-A2 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME Prolor Biotech Ltd. (IL) 2013-02-07 WO disclosed
US-8304386-B2 Long-acting growth hormone and methods of producing same Prolor Biotech, Inc. (IL) 2012-11-06 US disclosed
US-20120035101-A1 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME HCR INJECTION SPV, LLC, AS ADMINISTRATIVE AGENT 2012-02-09 US disclosed
US-20120015437-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME HCR INJECTION SPV, LLC, AS ADMINISTRATIVE AGENT 2012-01-19 US disclosed
US-8048849-B2 Long-acting polypeptides and methods of producing same Modigene, Inc. (IL) 2011-11-01 US disclosed
US-20100081614-A1 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME HCR INJECTION SPV, LLC, AS ADMINISTRATIVE AGENT 2010-04-01 US disclosed
US-20090312254-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME HCR INJECTION SPV, LLC, AS ADMINISTRATIVE AGENT 2009-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035101-A1 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME IGFBP1, IGFBP5, IGFBP2 NANP 2576/4885L3MBTL1 4162/4885SELL 1730/4885
US-20120015437-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME PGF, GNRHR, TSLP NANP 1835/4885L3MBTL1 4803/4885SELL 636/4885
US-20130184207-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING AND ADMINISTERING SAME PGF, GNRHR, LPXN NANP 1713/4885L3MBTL1 3708/4885SELL 1333/4885
US-10351615-B2 Methods of treatment with long-acting growth hormone IGFBP1, IGFBP5, IGFBP2 NANP 2621/4885L3MBTL1 3362/4885SELL 2141/4885
US-20090312254-A1 LONG-ACTING POLYPEPTIDES AND METHODS OF PRODUCING SAME PGF, GNRHR, TSLP NANP 1835/4885L3MBTL1 4803/4885SELL 636/4885
US-10221228-B2 Long-acting polypeptides and methods of producing and administering same PGF, GNRHR, LPXN NANP 1713/4885L3MBTL1 3708/4885SELL 1333/4885
US-11197915-B2 Long-acting polypeptides and methods of producing and administering same GHRHR, CRH, GHSR NANP 2296/4885L3MBTL1 4739/4885SELL 2432/4885
US-20100081614-A1 LONG-ACTING GROWTH HORMONE AND METHODS OF PRODUCING SAME GHRHR, LHCGR, GNRHR NANP 998/4885L3MBTL1 4591/4885SELL 2778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.