SCHEMBL343284

SCHEMBL343284

CC(=O)c1cc(Br)cc(Br)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5A P35218 1/20 0.52
LMNA P02545 2/20 0.43
NOTUM Q6P988 1/20 0.38
PARP1 P09874 1/20 0.38
POLB P06746 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
MAOB P27338 5/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
MAOA P21397 1/20 0.37
NPC1 O15118 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
MEN1 O00255 1/20 0.36
HSD17B1 P14061 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15709749 0.94 CA5A (0.52) CA5ALMNANOTUMPARP1POLB
SCHEMBL29547990 0.87 TPMT (0.46) CA5ALMNAMAPTHPGDRAB9A
SCHEMBL7786069 0.87 TPMT (0.46) CA5ALMNAMAPTHPGDRAB9A
SCHEMBL201236 0.85 CA5A (0.70) CA5ALMNAMAOBHPGDKMT2A
SCHEMBL7014559 0.85 POLB (0.47) CA5ALMNAPOLBHCAR2MAPT
SCHEMBL17922593 0.84 CA5A (0.43) CA5ALMNANOTUMPARP1POLB
SCHEMBL6246571 0.84 TPMT (0.43) CA5ALMNANOTUMMAOBMAPT
SCHEMBL17635528 0.84 CA5A (0.43) CA5ALMNANOTUMPARP1MAOB
SCHEMBL1764905 0.84 CES2 (0.44) CA5ALMNANOTUMMAOBHPGD
SCHEMBL200586 0.84 CA5A (0.43) CA5ALMNANOTUMPARP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
US-20240317672-A1 POLYCARBOXYLATE COMPOUND, RESIST COMPOSITION COMPRISING THE SAME AND METHOD OF FORMING PATTERN USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-09-26 US disclosed
WO-2024178004-A2 THERAPEUTIC COMPOUNDS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-08-29 WO disclosed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN disclosed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN disclosed
CN-113811531-B Phenanthroline compound and organic light-emitting device comprising same 株式会社进雄产业 2024-08-06 CN disclosed
WO-2024121709-A1 PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS PFIZER INC. (US) 2024-06-13 WO disclosed
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid ADIONICS (FR) 2023-08-22 US disclosed
US-20230065953-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
US-20220324835-A1 INHIBITORS OF CBL-B AND METHODS OF USE THEREOF NURIX THERAPEUTICS, INC. 2022-10-13 US disclosed
US-4870109-A ANIMAL HUSBANDRY ELI LILLY AND COMPANY (US) 1989-09-26 US disclosed
EP-0317275-A2 Control of ectoparasites BRITISH TECHNOLOGY GROUP USA INC. (US) 1989-05-24 EP disclosed
US-4754047-A ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1988-06-28 US disclosed
US-4522822-A Phenylethane derivatives and acid addition salts thereof for increasing lean meat deposition and/or improving lean meat to fat ratio in warm blooded animals AMERICAN CYANAMID COMPANY (US) 1985-06-11 US disclosed
US-4501751-A Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby AMERICAN CYANAMID COMPANY (US) 1985-02-26 US disclosed
EP-0026298-B1 METHOD FOR PROMOTING GROWTH AND REDUCING FAT IN ANIMALS USING PHENYLETHANOLAMINE DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1984-04-18 EP disclosed
US-4407819-A ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1983-10-04 US disclosed
US-4404222-A Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby AMERICAN CYANAMID COMPANY (US) 1983-09-13 US disclosed
EP-0026298-A1 Method for promoting growth and reducing fat in animals using phenylethanolamine derivatives AMERICAN CYANAMID COMPANY (US) 1981-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230065953-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES GLRX3, TARS2, CYP4F3 CA5A 1956/4885LMNA 3475/4885NOTUM 1780/4885
US-20240317672-A1 POLYCARBOXYLATE COMPOUND, RESIST COMPOSITION COMPRISING THE SAME AND METHOD OF FORMING PATTERN USING THE SAME SLC16A1, SLC11A2, ASS1 CA5A 454/4885LMNA 1672/4885NOTUM 364/4885
US-11731933-B2 Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid AQP3, AQP1, AQP4 CA5A 4068/4885LMNA 1748/4885NOTUM 1414/4885
US-20220324835-A1 INHIBITORS OF CBL-B AND METHODS OF USE THEREOF CBLB, CBL, CBLC CA5A 4481/4885LMNA 2103/4885NOTUM 3479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.